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Documentos Principais

Y0000538

Dexamethasone isonicotinate

European Pharmacopoeia (EP) Reference Standard

Sinônimo(s):

Dexamethasone 21-isonicotinate

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About This Item

Fórmula empírica (Notação de Hill):
C28H32FNO6
Número CAS:
Peso molecular:
497.56
Código UNSPSC:
41116107
NACRES:
NA.24

grau

pharmaceutical primary standard

família API

dexamethasone

fabricante/nome comercial

EDQM

aplicação(ões)

pharmaceutical (small molecule)

Formato

neat

temperatura de armazenamento

2-8°C

cadeia de caracteres SMILES

F[C@@]21[C@H]([C@H]4[C@@]([C@@]([C@@H](C4)C)(O)C(=O)COC(=O)c5ccncc5)(C[C@@H]2O)C)CCC3=CC(=O)C=C[C@@]31C

InChI

1S/C28H32FNO6/c1-16-12-21-20-5-4-18-13-19(31)6-9-25(18,2)27(20,29)22(32)14-26(21,3)28(16,35)23(33)15-36-24(34)17-7-10-30-11-8-17/h6-11,13,16,20-22,32,35H,4-5,12,14-15H2,1-3H3/t16-,20+,21+,22+,25+,26+,27+,28+/m1/s1

chave InChI

BQTXJHAJMDGOFI-NJLPOHDGSA-N

Descrição geral

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicação

Dexamethasone isonicotinate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Embalagem

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Outras notas

Sales restrictions may apply.

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Jorge Elizondo-Rodriguez et al.
Foot & ankle international, 34(1), 8-14 (2013-02-07)
The objective of this study was to compare intramuscularly applied botulinum toxin A (BTX-A) in the gastroc-soleus complex with intralesional steroids for the treatment of plantar fasciitis. The patients were randomly divided into 2 groups according to the treatment received.
[Notes on the disaster in Bhopal].
W F Diller
Deutsche medizinische Wochenschrift (1946), 110(45), 1749-1751 (1985-11-08)
P L Toutain et al.
Journal of veterinary pharmacology and therapeutics, 5(1), 33-43 (1982-03-01)
The pharmacokinetics of Dexamethasone (DXM) was studied in four cows all of which received DXM alcohol and DXM 21 isonicotinate (as a solution) by the intravenous and intramuscular routes. Concentrations of DXM and cortisol were determined using high performance liquid
Thomas Wittek et al.
Berliner und Munchener tierarztliche Wochenschrift, 118(3-4), 140-149 (2005-04-05)
The objective of the study was to describe the effects of a short acting glucocorticoid which was administered immediately after parturition in dairy cows on haematological, immunologic and metabolic parameters. The study was performed on 104 cows, 52 cows received
D Tainturier et al.
Journal of dairy science, 65(10), 1921-1924 (1982-10-01)
Passage of dexamethasone from plasma to milk in five lactating dairy cows after an intravenous injection was evaluated by a high performance liquid chromatographic technique for measurement of concentrations in blood plasma and milk. The dexamethasone ester was 21-isonicotinate as

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