1176506

Dexamethasone acetate

United States Pharmacopeia (USP) Reference Standard

• Sinônimo(s): Dexamethasone 21-acetate, 9α-Fluoro-16α-methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione-21-acetate, 9α-Fluoro-16α-methylprednisolone-21-acetate, Prednisolone F acetate
• Fórmula empírica (Notação de Hill): C₂₄H₃₁FO₆
• Número CAS: 1177-87-3
• Peso molecular: 434.50
• Beilstein: 2342608
• Número MDL: MFCD00027407
• Código UNSPSC: 41116107
• ID de substância PubChem: 329749549
• NACRES: NA.24

Propriedades

• fonte biológica: synthetic
• grau: pharmaceutical primary standard
• Agency: USP
• pressão de vapor: <0.0000001 kPa ( 25 °C)
• família API: dexamethasone
• forma: powder
• embalagem: pkg of 200 mg
• fabricante/nome comercial: USP
• cor: white
• pf: 460.4-464 °F (238—240°C)
• solubilidade: acetone: freely soluble; dichloromethane: slightly soluble; methanol: freely soluble; water: practically insoluble
• aplicação(ões): pharmaceutical (small molecule)
• formato: neat
• temperatura de armazenamento: 2-8°C
• cadeia de caracteres SMILES: [H][C@@]12CCC3=CC(=O)C=C[C@]3(C)[C@@]1(F)[C@@H](O)C[C@@]4(C)[C@@]2([H])C[C@@H](C)[C@]4(O)C(=O)COC(C)=O
• InChI: 1S/C24H31FO6/c1-13-9-18-17-6-5-15-10-16(27)7-8-21(15,3)23(17,25)19(28)11-22(18,4)24(13,30)20(29)12-31-14(2)26/h7-8,10,13,17-19,28,30H,5-6,9,11-12H2,1-4H3/t13-,17+,18+,19+,21+,22+,23+,24+/m1/s1
• chave InChI: AKUJBENLRBOFTD-RPRRAYFGSA-N
• Informações sobre genes: human ... NR3C1(2908)

Descrição

Descrição geral

Dexamethasone acetate (Decadron-LA) belongs to the class of long-acting glucocorticoids, commonly used as a pharmaceutical ingredient in creams, ointments, microemulsions, lotions, aerosols, etc.
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicação

Dexamethasone acetate USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Betamethasone Acetate
• Ciprofloxacin and Dexamethasone Otic Suspension
• Dexamethasone
• Dexamethasone Acetate
• Dexamethasone Acetate Injectable Suspension

Nota de análise

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Outras notas

Sales restrictions may apply.

Informações de segurança

• Pictogramas: GHS08
• Palavra indicadora: Danger
• Frases de perigo: H360FD
• Declarações de precaução: P201 - P202 - P280 - P308 + P313 - P405 - P501
• Classificações de perigo: Repr. 1B
• Código de classe de armazenamento: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable