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Documentos Principais

Y0000453

Oxycodone impurity D

European Pharmacopoeia (EP) Reference Standard

Sinônimo(s):

14-Hydroxycodeinone, (5α)-7,8-Didehydro-4,5-epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one

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About This Item

Fórmula empírica (Notação de Hill):
C18H19NO4
Número CAS:
Peso molecular:
313.35
Código UNSPSC:
41116107
NACRES:
NA.24

grau

pharmaceutical primary standard

família API

oxycodone

fabricante/nome comercial

EDQM

controle de medicamentos

regulated under CDSA - not available from Sigma-Aldrich Canada

aplicação(ões)

pharmaceutical (small molecule)

Formato

neat

temperatura de armazenamento

2-8°C

cadeia de caracteres SMILES

N1([C@H]2[C@]3([C@@]4(C(Oc5c4c(ccc5OC)C2)C(=O)C=C3)CC1)O)C

InChI

1S/C18H19NO4/c1-19-8-7-17-14-10-3-4-12(22-2)15(14)23-16(17)11(20)5-6-18(17,21)13(19)9-10/h3-6,13,16,21H,7-9H2,1-2H3/t13-,16?,17+,18-/m1/s1

chave InChI

YYCRAERBSFHMPL-FSFXSCMFSA-N

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Descrição geral

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicação

Oxycodone impurity D EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Embalagem

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Outras notas

Sales restrictions may apply.

Pictogramas

Skull and crossbonesHealth hazard

Palavra indicadora

Danger

Frases de perigo

Classificações de perigo

Acute Tox. 2 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Muta. 1B

Código de classe de armazenamento

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

Classe de risco de água (WGK)

WGK 3


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D L Lister et al.
FEMS microbiology letters, 181(1), 137-144 (1999-11-24)
A biotransformation mixture which contained codeine and washed cells of Pseudomonas putida M10 gave rise to a number of transformation products that are of clinical importance which included hydrocodone, dihydrocodeine and 14beta-hydroxycodeine. Incubations with the same organism and codeinone gave
D López et al.
The Journal of organic chemistry, 65(15), 4671-4678 (2000-08-26)
The photooxidation of thebaine (3) with a sun lamp affords two main products: hydrodibenzofuran 10 (major) and benzofuran 11 (minor). The latter compound becomes predominant if a Hg lamp is used instead of a sun lamp. The formation of 10
A Szentesi et al.
Analytical and bioanalytical chemistry, 374(3), 427-431 (2002-10-10)
A negative Cotton effect is observed in the circular dichroism (CD) spectra of 6-oxo-morphinans in the wavelength range of n-pi* electron transitions. 6-oxo-Morphinans can be transformed into oxime derivatives with hydroxylamine and after oxime formation the CD spectra are significantly

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