C9394

Chlorhexidine digluconate solution

20% in H₂O

• Sinônimo(s): Bis(p-chlorophenyl)diguanidohexane digluconate, 1,6-Bis(N⁵-[p-chlorophenyl]-N¹-biguanido)hexane; 1,1′-Hexamethylenebis(5-[p-chlorophenyl]biguanide)
• Número CAS: 18472-51-0
• Número MDL: MFCD00083599
• Código UNSPSC: 51102829
• ID de substância PubChem: 329775206
• NACRES: NA.85

Propriedades

• forma: liquid
• concentração: 20% in H₂O
• solubilidade: water: soluble 50 % (w/v)
• densidade: 1.06 g/mL at 25 °C (lit.)
• espectro de atividade do antibiótico: Gram-negative bacteria; Gram-positive bacteria
• Modo de ação: cell membrane | interferes
• temperatura de armazenamento: 2-8°C
• cadeia de caracteres SMILES: OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O.Clc1ccc(NC(=N)NC(=N)NCCCCCCNC(=N)NC(=N)Nc2ccc(Cl)cc2)cc1
• InChI: 1S/C22H30Cl2N10.2C6H12O7/c23-15-5-9-17(10-6-15)31-21(27)33-19(25)29-13-3-1-2-4-14-30-20(26)34-22(28)32-18-11-7-16(24)8-12-18;2*7-1-2(8)3(9)4(10)5(11)6(12)13/h5-12H,1-4,13-14H2,(H5,25,27,29,31,33)(H5,26,28,30,32,34);2*2-5,7-11H,1H2,(H,12,13)/t;2*2-,3-,4+,5-/m.11/s1
• chave InChI: YZIYKJHYYHPJIB-UUPCJSQJSA-N

Descrição

Aplicação

Chlorhexidine has been used to study how essential oils improve skin antisepsis when combined with chlorhexidine digluconate and is used for skin permeation studies . Chronic rinsing with chlorhexidine has been shown to decrease the saltiness of NaCl and the bitterness of quinine.

Used to study mechanism of membrane dysruption by bis(biguanide) molecules.

Ações bioquímicas/fisiológicas

Cationic broad-spectrum antimicrobial agent belonging to the bis(biguanide) family. Its mechanism of action involves destabilization of the outer bacterial membrane. It is used primarily as a topical antiseptic/disinfectant in wound healing, at catheterization sites, in various dental applications and in surgical scrubs.

Outras notas

Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage. Light sensitive.

Informações de segurança

• Pictogramas: GHS05,GHS09
• Palavra indicadora: Danger
• Frases de perigo: H318,H410
• Declarações de precaução: P273 - P280 - P305 + P351 + P338 - P391 - P501
• Classificações de perigo: Aquatic Acute 1 - Aquatic Chronic 2 - Eye Dam. 1
• Código de classe de armazenamento: 12 - Non Combustible Liquids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: Eyeshields, Faceshields, Gloves, multi-purpose combination respirator cartridge (US)