PHR2408

N-Nitrosodiethylamine (NDEA)

Pharmaceutical Secondary Standard; Certified Reference Material

• Sinônimo(s): N-Nitrosodiethylamine, Diethylnitrosamine
• Fórmula linear: (C₂H₅)₂NNO
• Número CAS: 55-18-5
• Peso molecular: 102.14
• Beilstein: 1744991
• Número MDL: MFCD00013890
• Código UNSPSC: 41116107
• NACRES: NA.24

Propriedades

• grau: certified reference material; pharmaceutical secondary standard
• Nível de qualidade: 300
• Agency: traceable to USP 1466652
• forma: liquid
• Certificado de análise (CofA): current certificate can be downloaded
• embalagem: pkg of 1 g
• pb: 177 °C (lit.)
• densidade: 0.95 g/mL (lit.)
• aplicação(ões): pharmaceutical
• temperatura de armazenamento: 2-30°C
• cadeia de caracteres SMILES: CCN(CC)N=O
• InChI: 1S/C4H10N2O/c1-3-6(4-2)5-7/h3-4H2,1-2H3
• chave InChI: WBNQDOYYEUMPFS-UHFFFAOYSA-N

Descrição

Descrição geral

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Aplicação

N-Nitrosodiethylamine (NDEA) pharmaceutical secondary referencestandard is used to determine NDEA impurity in:

• Lisinopril API and its final product
• Sitagliptin and metformin hydrochlorideimmediate and extended-release formulations

These Secondary Standards are qualified as Certified ReferenceMaterials. These are suitable for use in several analytical applicationsincluding but not limited to pharma release testing, pharma method developmentfor qualitative and quantitative analyses, food and beverage quality controltesting, and other calibration requirements.

Nota de análise

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Outras notas

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Nota de rodapé

To see an example of a Certificate of Analysis for this material enter LRAC4356 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Produtos recomendados

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Informações de segurança

• Pictogramas: GHS06,GHS08
• Palavra indicadora: Danger
• Frases de perigo: H301,H350,H412
• Declarações de precaução: P202 - P264 - P270 - P273 - P280 - P301 + P310
• Classificações de perigo: Acute Tox. 3 Oral - Aquatic Chronic 3 - Carc. 1B
• Código de classe de armazenamento: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable