40334
N-Nitrosodiethylamine (NDEA) solution
certified reference material, 5000 μg/mL in methanol
Sinônimo(s):
Diethylnitrosamine
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About This Item
Produtos recomendados
grau
certified reference material
TraceCERT®
linha de produto
TraceCERT®
Certificado de análise (CofA)
current certificate can be downloaded
embalagem
ampule of 1 mL
concentração
5000 μg/mL in methanol
técnica(s)
HPLC: suitable
gas chromatography (GC): suitable
aplicação(ões)
cleaning products
cosmetics
environmental
food and beverages
personal care
formato
single component solution
temperatura de armazenamento
2-8°C
InChI
1S/C4H10N2O/c1-3-6(4-2)5-7/h3-4H2,1-2H3
chave InChI
WBNQDOYYEUMPFS-UHFFFAOYSA-N
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Descrição geral
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
N-Nitrosodiethylamine belongs to the group of toxic nitrosamines, known to show carcinogenic, mutagenic, and hepatotoxic properties. It is formed as a byproduct during food processing, pharmaceutical processing, and water treatment. As a result, they are generally found in water, fish, meat, drug substances, etc.
N-Nitrosodiethylamine belongs to the group of toxic nitrosamines, known to show carcinogenic, mutagenic, and hepatotoxic properties. It is formed as a byproduct during food processing, pharmaceutical processing, and water treatment. As a result, they are generally found in water, fish, meat, drug substances, etc.
Aplicação
The CRM can be used as follows:
- Simultaneous analysis of N-nitrosodiethanolamine, N-nitrosodiethylamine, triethanolamine, diethanolamine in cosmetic samples using liquid chromatography-electrospray ionization-tandem mass spectrometry (LC-ESI-MS/MS)
- Solid phase extraction of N-nitrosodimethylamine and N-nitrosomethylethylamine from eight sartans, ranitidine, and metformin and also the fortified products of these drugs, for quantification by gas chromatography-tandem mass spectrometry (GC-MS/MS)
- Multi-residue analysis of seven restricted nitrosamines in two body creams and two shower gel samples by vortex-assisted reversed-phase dispersive liquid-liquid microextraction (VA-RP-DLLME) and liquid chromatography-mass spectrometry (LC-MS)
- Quantitative analysis of four nitrosamines in four sartan drug substances— candesartan cilexetil, olmesartan medoxomi, irbesartan, and valsartan, by gas chromatography-tandem mass spectrometry (GC-MS/MS)
- Determination of eight volatile nitrosamines in 28 popular meat product samples using ultrasonic solvent extraction combined with solid phase microextraction (SPME) and GC-MS
Outras notas
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Informações legais
TraceCERT is a registered trademark of Merck KGaA, Darmstadt, Germany
Palavra indicadora
Danger
Frases de perigo
Declarações de precaução
Classificações de perigo
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Carc. 1B - Flam. Liq. 2 - STOT SE 1
Órgãos-alvo
Eyes,Central nervous system
Código de classe de armazenamento
3 - Flammable liquids
Classe de risco de água (WGK)
WGK 3
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Protocolos
US EPA Method 8270 (Appendix IX): GC Analysis of Semivolatiles on Equity®-5 (30 m x 0.25 mm I.D., 0.50 μm)
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