PHR1224

Aminocaproic acid

Pharmaceutical Secondary Standard; Certified Reference Material

• Sinônimo(s): 6-Aminocaproic acid, ε-Aminocaproic acid, 6-Aminohexanoic acid, EACA
• Fórmula linear: H₂N(CH₂)₅CO₂H
• Número CAS: 60-32-2
• Peso molecular: 131.17
• Beilstein: 906872
• Número CE: 200-469-3
• Número MDL: MFCD00008238
• Código UNSPSC: 41116107
• ID de substância PubChem: 329823230
• NACRES: NA.24

Propriedades

• grau: certified reference material; pharmaceutical secondary standard
• Nível de qualidade: 300
• Agency: traceable to Ph. Eur. A0420000; traceable to USP 1021000
• família API: aminocaproic acid
• Certificado de análise (CofA): current certificate can be downloaded
• técnica(s): HPLC: suitable; gas chromatography (GC): suitable
• pf: 207-209 °C (dec.) (lit.)
• aplicação(ões): pharmaceutical (small molecule)
• Formato: neat
• temperatura de armazenamento: 2-30°C
• cadeia de caracteres SMILES: NCCCCCC(O)=O
• InChI: 1S/C6H13NO2/c7-5-3-1-2-4-6(8)9/h1-5,7H2,(H,8,9)
• chave InChI: SLXKOJJOQWFEFD-UHFFFAOYSA-N
• Informações sobre genes: human ... PLAT(5327) , PLG(5340)

Descrição

Descrição geral

Aminocaproic acid is a synthetic inhibitor of fibrinolysis and is utilized for the control of excessive bleeding in patients with amegakaryocytic thrombocytopenia.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Aplicação

Aminocaproic acid may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by fluorimetry and in bulk and injectable forms using colorimetric method.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Ações bioquímicas/fisiológicas

Lysine analog. Promotes rapid dissociation of plasmin, thereby inhibiting the activation of plasminogen and subsequent fibrinolysis.

Lysine analog. Promotes rapid dissociation of plasmin, thereby inhibiting the activation of plasminogen and subsequent fibrinolysis. Reported to inhibit plasminogen binding to activated platelets. An early report indicated that it inhibits the activation of the first component of the complement system. Binds and inactivates Carboxypeptidase B.

Nota de análise

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Outras notas

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Nota de rodapé

To see an example of a Certificate of Analysis for this material enter LRAA9036 in the slot below. This is an example certificate only and may not be the lot that you receive.

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 2
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable