LIGHTOX25

LightOx^™25

≥95% (HPLC)

• Fórmula empírica (Notação de Hill): C₂₁H₂₁NO₂
• Número CAS: 2342579-17-1
• Peso molecular: 319.40
• Código UNSPSC: 12352101
• NACRES: NA.22

Propriedades

• Ensaio: ≥95% (HPLC)
• Formulário: powder
• temperatura de armazenamento: 2-8°C
• cadeia de caracteres SMILES: N1(CCCc2c1ccc(c2)C#Cc3ccc(cc3)C(=O)O)C(C)C
• InChI: 1S/C21H21NO2/c1-15(2)22-13-3-4-19-14-17(9-12-20(19)22)6-5-16-7-10-18(11-8-16)21(23)24/h7-12,14-15H,3-4,13H2,1-2H3,(H,23,24)
• chave InChI: OWPRYZBCLJMXGR-UHFFFAOYSA-N

Descrição

Aplicação

Fluorescence microscopy, fluorescent retinoid binding assay, fluorescence spectroscopy.

Ações bioquímicas/fisiológicas

Strong ligand for retinoic acid receptor proteins

Características e benefícios

LightOx25 is a synthetic analogue of all-trans-retinoic acid (ATRA), that exhibits solvatochromatic fluorescence emission when excited with UV or 405 nm light. The compound is a strong ligand for the retinoic acid receptor proteins (RARs) and related cellular retinoic acid binding proteins (CRABPI/II) and can, therefore, be used as a replacement for ATRA in cellular assays involving retinoid signaling processes. LightOx25 can be utilised to study retinoid behaviour using fluorescence microscopy, employed in a competitive fluorometric ligand-binding assay for direct determination of the strength of binding of non-fluorescent retinoids to a protein target, and as a fluorophore in fluorescence spectroscopy.

Product can be used with our line of photoreactors: Including Penn PhD (Z744035) & SynLED 2.0 (Z744080)

Outras notas

Chemical Equivalency 1ea=1mg

Informações legais

LightOx is a trademark of LightOx Ltd.

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable