73577

Scutellarin

analytical standard

• Sinônimo(s): 4′,5,6,7-Tetrahydroxyflavone 7-glucuronide, 5,6-Dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-1-benzopyran-7-yl-β-D-glucopyranosiduronic acid, 7-(β-D-Glucopyranuronosyloxy)-5,6-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one, Breviscapin, Scutellarein-7-O-β-D-glucuronide
• Fórmula empírica (Notação de Hill): C₂₁H₁₈O₁₂
• Número CAS: 27740-01-8
• Peso molecular: 462.36
• Beilstein: 71779
• Número MDL: MFCD01861503
• Código UNSPSC: 85151701
• ID de substância PubChem: 329765055
• NACRES: NA.24

Propriedades

• grau: analytical standard
• Nível de qualidade: 100
• Ensaio: ≥98.0% (HPLC)
• prazo de validade: limited shelf life, expiry date on the label
• técnica(s): HPLC: suitable; gas chromatography (GC): suitable
• aplicação(ões): food and beverages
• formato: neat
• temperatura de armazenamento: 2-8°C
• cadeia de caracteres SMILES: O[C@@H]1[C@@H](O)[C@@H](O[C@@H]([C@H]1O)C(O)=O)Oc2cc3OC(=CC(=O)c3c(O)c2O)c4ccc(O)cc4
• InChI: 1S/C21H18O12/c22-8-3-1-7(2-4-8)10-5-9(23)13-11(31-10)6-12(14(24)15(13)25)32-21-18(28)16(26)17(27)19(33-21)20(29)30/h1-6,16-19,21-22,24-28H,(H,29,30)/t16-,17-,18+,19-,21+/m0/s1
• chave InChI: DJSISFGPUUYILV-ZFORQUDYSA-N

Descrição

Descrição geral

Scutellarin is flavone glucuronide and an active ingredient of breviscapine. It is widely used for the treatment of cerebral infarction, coronary heart disease and angina pectoris.

Aplicação

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Scutellarin may be used as an analytical reference standard for the quantification of the analyte in plasma samples using different chromatography techniques.

Ações bioquímicas/fisiológicas

Scutellarin is a flavonoid that exhibits a number of cardio- and neuro-protective effects. Scutellarin inhibits p38 activity, ERK phosphorylation, and TGF-β expression and fibrosis in a rat myocardial infarct model. In a cerebral ischemia-reperfusion model, the compound reduced infarct volume and neurological deficits by increasing eNOS expression while inhibiting the induction of iNOS.

Embalagem

Bottomless glass bottle. Contents are inside inserted fused cone.

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable