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Key Documents

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Supelco

Drometrizole trisiloxane

analytical standard

Sinônimo(s):

2-(2H-Benzotriazol-2-yl)-4-methyl-6-{2-methyl-3-{1,3,3,3-tetramethyl-1-[(trimethylsilyl)oxy]disiloxanyl}propyl}phenol, Silatrizole

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About This Item

Fórmula empírica (Notação de Hill):
C24H39N3O3Si3
Número CAS:
Peso molecular:
501.84
Beilstein:
11343300
Número MDL:
Código UNSPSC:
41116107
ID de substância PubChem:
NACRES:
NA.24

grau

analytical standard

Nível de qualidade

Ensaio

≥98.0% (HPLC)

prazo de validade

limited shelf life, expiry date on the label

técnica(s)

HPLC: suitable
gas chromatography (GC): suitable

aplicação(ões)

cleaning products
cosmetics
environmental
food and beverages
personal care

formato

neat

cadeia de caracteres SMILES

CC(Cc1cc(C)cc(c1O)-n2nc3ccccc3n2)C[Si](C)(O[Si](C)(C)C)O[Si](C)(C)C

InChI

1S/C24H39N3O3Si3/c1-18-14-20(15-19(2)17-33(9,29-31(3,4)5)30-32(6,7)8)24(28)23(16-18)27-25-21-12-10-11-13-22(21)26-27/h10-14,16,19,28H,15,17H2,1-9H3

chave InChI

HUVYTMDMDZRHBN-UHFFFAOYSA-N

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Descrição geral

Drometrizole trisiloxane (DRT) belongs to the lipophilic benzotriazole derivative class of compounds commonly utilized in sunscreen cosmetics.

Aplicação

DRT may be used as a reference standard for the determination of DRT in:
  • Active pharmaceutical ingredients (APIs), formulations and stability samples by reversed phase ultra-high performance liquid chromatography (RP-UPLC) coupled to electrospray ionization-quadrupole time-of-flight tandem mass spectrometry (ESI-QTOF-MS/MS).
  • Suncare formulations by high performance liquid chromatography (HPLC) with ultraviolet (UV) detection.
  • Cosmetic products by LC-UV.
  • Sewage sludge samples by QuEChERS (quick, easy, cheap, effective, rugged, and safe) extraction procedure and gas chromatography combined with MS/MS.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Embalagem

Bottomless glass bottle. Contents are inside inserted fused cone.

Produtos recomendados

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Frases de perigo

Declarações de precaução

Classificações de perigo

Aquatic Chronic 4

Código de classe de armazenamento

10 - Combustible liquids

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable


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Certificados de análise (COA)

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A reliable and environmentally-friendly liquid-chromatographic method for multi-class determination of fat-soluble UV filters in cosmetic products.
Chisvert A, et al.
Analytica Chimica Acta, 790(1-2), 61-67 (2013)
Development and optimization of a QuEChERS-GC-MS/MS methodology to analyse ultraviolet-filters and synthetic musks in sewage sludge.
Ramos S, et al.
The Science of the Total Environment, 790(1-2), 61-67 (2018)
A Sensitive, Stability indicating UPLC method for the identification and characterization of forced degradation products for Drometrizole Trisiloxane through MSn studies.
Babu MA, et al.
Journal of Applied Pharmaceutical Science, 8(06), 065-074 (2018)
Determination of sixteen UV filters in suncare formulations by high-performance liquid chromatography.
Schakel DJ, et al.
Journal of Chromatography A, 1049(1-2), 127-130 (2004)

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