62862

Dodecilsulfato de sódio

≥90% ((Assay))

• Sinônimo(s): Dodecil sulfato de sódio, Dodecilsulfato, Lauril sulfato, Lauril sulfato de sódio, SDS
• Fórmula linear: CH₃(CH₂)₁₁OSO₃Na
• Número CAS: 151-21-3
• Peso molecular: 288.38
• Beilstein: 3599286
• Número CE: 205-788-1
• Número MDL: MFCD00036175
• Código UNSPSC: 12161900
• eCl@ss: 39093306
• ID de substância PubChem: 57651912
• NACRES: NA.21

Propriedades

• descrição: anionic; 62
• Nível de qualidade: 100
• Ensaio: ≥90% ((Assay))
• peso molecular: 288.38 g/mol
• técnica(s): LC/MS: suitable; electrophoresis: suitable; protein quantification: suitable
• pf: 204-207 °C (lit.)
• solubilidade: water: soluble
• HLB: 40
• cadeia de caracteres SMILES: [Na+].CCCCCCCCCCCCOS([O-])(=O)=O
• InChI: 1S/C12H26O4S.Na/c1-2-3-4-5-6-7-8-9-10-11-12-16-17(13,14)15;/h2-12H2,1H3,(H,13,14,15);/q;+1/p-1
• chave InChI: DBMJMQXJHONAFJ-UHFFFAOYSA-M

Descrição

Descrição geral

Sodium dodecyl sulfate (SDS), also known as sodium lauryl sulfate (SLS), has an alkyl tail of 12 carbon atoms attached to a sulfate group. It is an anionic surfactant due to the negative charge of its sulfate group.

Aplicação

Detergente aniônico

Sodium dodecyl sulfate has been used:

• to prepare Chit for coating the Janus micromotors for the synthesis of magnesium (Mg)-based micromotors
• as a component in low salt lysis buffer to lyse the edible bird’s nest (EBN) treated cells for western blot analysis
• in the preparation of decellularizing solution to scale down and decellularize skin fragments

Ações bioquímicas/fisiológicas

Sodium dodecyl sulfate (SDS) is frequently used as an ingredient in a wide range of products, including pharmaceuticals, and product formulations. It is broadly used in several applications including electrophoresis for the separation of proteins and as an organic template for preparing periodic mesoporous organosilica nanospheres. SDS is also used in the solubilization of proteins and lipids, as well as drugs, dispersion of functionalized carbon nanotubes and graphene sheets, and gas hydrate formation. It is commonly used for the quick disruption of biological membranes. Due to its ability to disrupt the tissue architecture, SDS is preferred in several nucleic acid purification reagents. SDS has very low solubility in high salt, and chaotropic solutions and is readily precipitable in the presence of potassium salts, so it is usually not added to guanidinium buffers.

Características e benefícios

• Assay: ≥90%
• Suitable for LC/MS, electrophoresis, and protein quantification
• Inhibits RNase and deoxyribonuclease (DNase) activity

Informações de segurança

• Pictogramas: GHS02,GHS05,GHS07
• Palavra indicadora: Danger
• Frases de perigo: H228,H302 + H332,H315,H318,H335,H412
• Declarações de precaução: P210 - P273 - P280 - P301 + P312 - P304 + P340 + P312 - P305 + P351 + P338
• Classificações de perigo: Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Flam. Sol. 2 - Skin Irrit. 2 - STOT SE 3
• Órgãos-alvo: Respiratory system
• Código de classe de armazenamento: 4.1B - Flammable solid hazardous materials
• Classe de risco de água (WGK): WGK 2
• Ponto de fulgor (°F): 338.0 °F
• Ponto de fulgor (°C): 170 °C
• Equipamento de proteção individual: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges