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55016

Supelco

Theaflavin

analytical standard

Sinônimo(s):

3,4,5-Trihydroxy-1,8-bis[(2R,3R)-3,5,7-trihydroxy-2-chromanyl]-6-benzo[7]annulenone, 3,4,6-Trihydroxy-1,8-bis(3α,5,7-trihydroxy-2α-chromanyl)-5H-benzocyclohepten-5-one

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About This Item

Fórmula empírica (Notação de Hill):
C29H24O12
Número CAS:
4670-05-7
Peso molecular:
564.49
Número MDL:
MFCD03427500
Código UNSPSC:
41116107
ID de substância PubChem:
329758072
NACRES:
NA.24

grau

analytical standard

Nível de qualidade

100

Ensaio

≥90.0% (HPLC)

técnica(s)

HPLC: suitable
gas chromatography (GC): suitable

aplicação(ões)

food and beverages

Formato

neat

temperatura de armazenamento

−20°C

cadeia de caracteres SMILES

O[C@@H]1Cc2c(O)cc(O)cc2O[C@@H]1C3=Cc4c(cc(O)c(O)c4C(=O)C(O)=C3)[C@H]5Oc6cc(O)cc(O)c6C[C@H]5O

InChI

1S/C29H24O12/c30-11-3-17(32)15-8-21(36)28(40-23(15)5-11)10-1-13-14(7-20(35)27(39)25(13)26(38)19(34)2-10)29-22(37)9-16-18(33)4-12(31)6-24(16)41-29/h1-7,21-22,28-33,35-37,39H,8-9H2,(H,34,38)/t21-,22-,28-,29-/m1/s1

chave InChI

IPMYMEWFZKHGAX-ZKSIBHASSA-N

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Descrição geral

Theaflavin is a polyphenol, naturally available in tea, which can mainly play a role in the inhibition of xanthine oxidase enzyme to yield uric acid. It can also find applications in reducing oxidative stress and can also act like scavengers of superoxide.

Aplicação

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Embalagem

Bottomless glass bottle. Contents are inside inserted fused cone.

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)

Escolha uma das versões mais recentes:

Certificados de análise (COA)

Lot/Batch Number
BCCD3318
BCBT3522

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Sigma-Aldrich

E4143

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Sigma-Aldrich

E3768

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Supelco

08108

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(−)-Gallocatechin gallate from green tea, ≥98% (HPLC)

Sigma-Aldrich

G6782

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Sigma-Aldrich

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Xueli Cao et al.
Journal of separation science, 34(19), 2611-2617 (2011-09-08)
An improved type-J counter-current chromatography (CCC) planet centrifuge with two spiral tube columns (volume 2×15 mL, β value 0.3-0.7, tubing 0.8 mm id) was developed and evaluated for its retention ability of four typical different solvent systems including heptane-methanol (1:1
Jie Yang et al.
AIDS research and human retroviruses, 28(11), 1498-1508 (2012-08-08)
We previously demonstrated that a commercially available natural product preparation with high content (>90%) of theaflavin derivatives (TFmix) exhibited potent anti-HIV activities. Here we developed a TFmix gel formulation as a topical microbicide candidate. The effect of TFmix on the
Andrew G Mercader et al.
Current medicinal chemistry, 19(25), 4324-4347 (2012-07-27)
Flavonoids have shown anticarcinogenic activity in cancer cell lines, animal models, and some human studies. Quantitative structure-activity relationship (QSAR) models have become useful tools for identification of promising lead compounds in anticancer drug development. However, epidemiological and clinical studies are
A Anandhan et al.
Neuroscience, 218, 257-267 (2012-05-29)
Evidence from clinical and experimental studies indicates that degeneration of nigrostriatal dopaminergic neurons is a pathological hallmark of Parkinson's disease (PD). The present study was designed to investigate the neuroprotective potential of theaflavin (TF) on oxidative stress, monoamine transporters and
Suchismita Mohanty et al.
Frontiers in bioscience (Scholar edition), 4, 300-320 (2011-12-29)
With phytochemicals executing a plethora of anti-tumor mechanisms, targeting the 'guardian angel' p53 appears to be a critical strategy to energize the process of cancer therapeutics. Regulation of anti-tumor p53 functions by dietary plant polyphenols particularly black tea and its
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