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Supelco

trans-2-Tetradecenoyl-L-carnitine

analytical standard

Sinônimo(s):

(2R)-3-Carboxy-N,N,N-trimethyl-2-[[(2E)-1-oxo-2-tetradecen-1-yl]oxy]-1-propanaminium inner salt, trans-2-Myristenoyl-L-carnitine, C14:1-Carnitine

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About This Item

Fórmula empírica (Notação de Hill):
C21H39NO4
Peso molecular:
369.54
Código UNSPSC:
41116107
NACRES:
NA.24

grau

analytical standard

Ensaio

≥95.0% (LC/MS)

atividade óptica

[α]/D -12±2°, c = 0.1 in methanol

prazo de validade

limited shelf life, expiry date on the label

aplicação(ões)

clinical testing

formato

neat

temperatura de armazenamento

−20°C

cadeia de caracteres SMILES

[O-]C(C([H])([H])[C@](OC(/C([H])=C([H])/C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=O)([H])C([H])([H])[N+](C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])=O

Descrição geral

trans-2-Tetradecenoyl-L-carnitine, belonging to the class of acylcarnitines, serves as a specific diagnostic metabolite biomarker, which increases in very long-chain acyl CoA dehydrogenase (VLCAD) deficiency, existing as a long-chain β-oxidation defect in newborns.

Aplicação

trans-2-Tetradecenoyl-L-carnitine may be used as an analytical reference standard in the following:
  • Quantification of the analyte in biological samples using high-performance liquid chromatography coupled to tandem mass spectrometry (HPLC/MS/MS).
  • Quantification of the analyte in dried blood spots using chip-based nanoelectrospray source coupled with high resolution mass spectrometry (chip-based nanoESI- HRMS) and targeted liquid chromatography-tandem mass spectrometry (LC/MS/MS).

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable


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Differences between acylcarnitine profiles in plasma and bloodspots
Diekman FE, et al.
Molecular Genetics and Metabolism, 110(1-2), 116-121 (2013)

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