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Supelco

Oxfendazole

VETRANAL®, analytical standard

Sinônimo(s):

Methyl 5-(phenylsulfinyl)-benzimidazol-2-carbamate

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About This Item

Fórmula empírica (Notação de Hill):
C15H13N3O3S
Número CAS:
53716-50-0
Peso molecular:
315.35
Número CE:
258-714-5
Número MDL:
MFCD00801063
Código UNSPSC:
41116107
ID de substância PubChem:
329754866
NACRES:
NA.24

grau

analytical standard

Nível de qualidade

100

linha de produto

VETRANAL®

prazo de validade

limited shelf life, expiry date on the label

técnica(s)

HPLC: suitable
gas chromatography (GC): suitable

aplicação(ões)

forensics and toxicology
pharmaceutical (small molecule)

formato

neat

cadeia de caracteres SMILES

COC(=O)Nc1nc2cc(ccc2[nH]1)S(=O)c3ccccc3

InChI

1S/C15H13N3O3S/c1-21-15(19)18-14-16-12-8-7-11(9-13(12)17-14)22(20)10-5-3-2-4-6-10/h2-9H,1H3,(H2,16,17,18,19)

chave InChI

BEZZFPOZAYTVHN-UHFFFAOYSA-N

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Descrição geral

Oxfendazole is a benzimidazole anthelmintic drug, effective against cysticercosis, echinococcosis and fasciolosis.
Oxfendazole is a member of benzimidazole group of anthelmintics.

Aplicação

Oxfendazole may be used as a reference standard in the determination of oxfendazole in pharmaceutical preparations using reversed-phase high-performance liquid chromatography (RP-HPLC).
Oxfendazole may be used as an analytical reference standard for the determination of the analyte in bovine liver by liquid chromatography method.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Produtos recomendados

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Informações legais

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictogramas

Health hazardEnvironment
GHS08,GHS09

Palavra indicadora

Danger

Frases de perigo

H360D,H373,H410

Classificações de perigo

Aquatic Acute 1 - Aquatic Chronic 1 - Repr. 1B - STOT RE 2

Código de classe de armazenamento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)

Choose from one of the most recent versions:

Certificados de análise (COA)

Lot/Batch Number
BCCG5828
BCCB2008
BCCB2006
BCBT4620
BCBT4622

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L Moreno et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 50(10), 3819-3825 (2012-07-31)
Oxfendazole (OFZ) is efficacious for porcine cysticercosis at 30 mg/kg. OFZ is not registered to be used at this dose. The assessment of the OFZ and metabolites [(fenbendazole sulphone (FBZSO2), fenbendazole (FBZ)] plasma pharmacokinetic and tissue residue profiles after its
Cesar M Gavidia et al.
The American journal of tropical medicine and hygiene, 80(3), 367-372 (2009-03-10)
Cystic echinococosis (CE) is a public health problem caused by Echinococcus granulosus. We aimed to determine the efficacy of nitazoxanide (NTZ) and oxfendazole (OXF) against CE in naturally infected sheep. A total of 151 ewes were assigned to the following
Tine Moesgaard Iburg et al.
Veterinary parasitology, 190(3-4), 442-446 (2012-08-14)
The aim of the present study was to test histopathologically the hypothesis that the time for clearing Taenia solium cysts in muscle tissue of pigs following treatment with oxfendazole is cyst density dependent. A total of 248 cyst lesions in
Emmanuel Assana et al.
International journal for parasitology, 40(5), 515-519 (2010-02-09)
A pilot field trial of the TSOL18 vaccine was undertaken in Cameroon. Two hundred and forty, 2-3 month-old piglets were distributed to 114 individual households in pairs. Vaccinated animals received three immunisations with 200 microg TSOL18 plus 5 mg Quil
C S Sikasunge et al.
Veterinary parasitology, 158(1-2), 57-66 (2008-10-07)
The aim of this study was to assess the effect of treating Taenia solium infected pigs with oxfendazole (OFZ) on viability and clearance of cysticerci and the corresponding persistence of specific antibody isotypes (IgG(total), IgG1, IgG2 and IgA) and circulating
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