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Merck
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15256

Supelco

BSA+TMCS

for GC derivatization, LiChropur, 93.0-97.0% (GC)

Sinônimo(s):

Bis(trimethylsilyl)acetamide + Trimethylchlorosilane

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About This Item

Código UNSPSC:
41116105
ID de substância PubChem:
NACRES:
NA.22

grau

for GC derivatization

Nível de qualidade

Ensaio

93.0-97.0% (GC)

qualidade

LiChropur

composição

trimethylchlorosilane (minor component), 3.0-5.0% GC

adequação da reação

reagent type: derivatization reagent
reaction type: Silylations

técnica(s)

gas chromatography (GC): suitable

Descrição geral

BSA+TMCS combination, is one of the most commonly used silylating reagents. BSA is readily used for silylating a wide range of functional groups such as non-sterically hindered alcohols, amides, amines, amino acids, carboxylic acids, and enols. TMCS is a silylation catalyst always used with other silylation reagents to increase the reactivity in derivatization of alcohols, alkaloids, amines, biogenic amines, carboxylic acids, phenols, and steroids.

Aplicação

Learn more in the Product Information
Suitable for the derivatization of α-ketoacids, amines, amino acids, cycloserine, histamine and metabolites, phenylethylamines, phosphatidylserines and tryptamines. BSA+TMCS may be used as a derivatizing reagent for the determination of steryl glycosides in biodiesel using gas chromatography–mass spectrometry.
Suitable for the derivatization of a-ketoacids, amines, amino acids, cycloserine, histamine and metabolites, phenylethylamines, phosphatidylserines and tryptamines.

Características e benefícios

  • BSA+TMCS has good solvent properties and can function as a silylation reagent without additional solvents.        
  • Alternatively, the mixture is very soluble in most commonly used silylation solvents.        
  • This combination is extremely sensitive to moisture and should be handled under dry conditions.

Outras notas

Powerful silylation mixture with wide applicability
Reagent for trimethylsilyl diglyceride, trimethylsilyl (TMS) and trimethylsilyl oximes.

Informações legais

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

Palavra indicadora

Danger

Frases de perigo

Classificações de perigo

Acute Tox. 4 Oral - Flam. Liq. 2 - Skin Corr. 1A

Perigos de suplementos

Código de classe de armazenamento

3 - Flammable liquids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

53.6 °F - closed cup

Ponto de fulgor (°C)

12 °C - closed cup

Equipamento de proteção individual

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter


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Visite a Biblioteca de Documentos

P. Englmaier
Z. Anal. Chem., 324, 338-338 (1986)
J. Heberle et al.
Silylating Agents, 2nd ed. (1995)
Ashwin Unnikrishnan et al.
Nucleic acids research, 44(22), 10644-10661 (2016-09-09)
Aberrant stem cell-like gene regulatory networks are a feature of leukaemogenesis. The ETS-related gene (ERG), an important regulator of normal haematopoiesis, is also highly expressed in T-ALL and acute myeloid leukaemia (AML). However, the transcriptional regulation of ERG in leukaemic
D.R. Knapp
Handbook of Analytical Derivatization Reactions, 202-202 (1979)
D.L. Sondack et al.
Journal of Pharmacological Sciences, 62, 1344-1344 (1973)

Artigos

Results of a study involving the ability few Fluka silylating reagents to form GC-MS-compatible trimethylsilylmethyl derivatives of NSAIDs

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