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Documentos Principais

09236

Supelco

β-Amyrin

analytical standard

Sinônimo(s):

β-Amyrenol, Olean-12-en-3β-ol

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About This Item

Fórmula empírica (Notação de Hill):
C30H50O
Número CAS:
Peso molecular:
426.72
Beilstein:
2063468
Número CE:
Número MDL:
Código UNSPSC:
85151701
ID de substância PubChem:
NACRES:
NA.24

grau

analytical standard

Nível de qualidade

Ensaio

≥98.5% (HPLC)

prazo de validade

limited shelf life, expiry date on the label

técnica(s)

HPLC: suitable
gas chromatography (GC): suitable

aplicação(ões)

food and beverages

Formato

neat

cadeia de caracteres SMILES

[H][C@@]12CC(C)(C)CC[C@]1(C)CC[C@]3(C)C2=CC[C@]4([H])[C@@]5(C)CC[C@H](O)C(C)(C)[C@]5([H])CC[C@@]34C

InChI

1S/C30H50O/c1-25(2)15-16-27(5)17-18-29(7)20(21(27)19-25)9-10-23-28(6)13-12-24(31)26(3,4)22(28)11-14-30(23,29)8/h9,21-24,31H,10-19H2,1-8H3/t21-,22-,23+,24-,27+,28-,29+,30+/m0/s1

chave InChI

JFSHUTJDVKUMTJ-QHPUVITPSA-N

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Descrição geral

β-Amyrin belongs to the group of naturally occurring pentacyclic triterpenes, known for its anti-inflammatory, anti-microbial, anti-oxidative, and chemoprotective properties.

Aplicação

This analytical standard can also be used as follows:

  • Development and validation of two high-performance thin layer chromatography (HPTLC) methods to quantify four biomarkers— β-amyrin, β-sitosterol, lupeol, and ursolic acid in the ethanol extract of G. senegalensis leaves
  • Analysis of methanol extracts of leaf samples collected from five Ficus species by a novel HPTLC densitometric method, for the determination of β-amyrin, validated according to the International Conference on Harmonization (ICH) guidelines
  • Quantification of β-amyrin in the ethanolic extracts collected from two Maytenus species, M. obscura and M. parviflora by a validated HPTLC-densitometric method
  • Secondary metabolite profiling of various plant parts collected from 82 plants belonging to 21 different cannabis strains using gas chromatography-mass spectrometry (GC-MS) for sterols and terpenoids (mono-, sesqui-, tri-), and high-performance liquid chromatography (HPLC) with UV and mass spectrometric (MS) detection for flavonoids

Ações bioquímicas/fisiológicas

Triterpene that has broad-spectrum analgesic properties for which the underlying mechanism is poorly understood.

Embalagem

Bottomless glass bottle. Contents are inside inserted fused cone.

Pictogramas

Exclamation mark

Palavra indicadora

Warning

Frases de perigo

Declarações de precaução

Classificações de perigo

Acute Tox. 4 Oral

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)


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Lupeol phyproof® Reference Substance

PHL89722

Lupeol

Betulin ≥98%

Sigma-Aldrich

B9757

Betulin

Oleanolic acid ≥97%

Sigma-Aldrich

O5504

Oleanolic acid

Hederagenin ≥97% (HPLC)

Sigma-Aldrich

H3916

Hederagenin

Erythrodiol analytical standard

Supelco

09258

Erythrodiol

β-Amyrin induces angiogenesis in vascular endothelial cells through the Akt/endothelial nitric oxide synthase signaling pathway.
Ishii M, et al.
Biochemical and Biophysical Research Communications, 467(4), 676-682 (2015)
Separation and identification of some common isomeric plant triterpenoids by thin-layer chromatography and high-performance liquid chromatography.
Martelanc M, et al.
Journal of Chromatography A, 1216(38), 6662-6670 (2009)
Amit Rai et al.
The Plant journal : for cell and molecular biology, 90(4), 764-787 (2017-01-22)
Medicinal plants are a rich source of highly diverse specialized metabolites with important pharmacological properties. Until recently, plant biologists were limited in their ability to explore the biosynthetic pathways of these metabolites, mainly due to the scarcity of plant genomics
Cyril Brendolise et al.
The FEBS journal, 278(14), 2485-2499 (2011-05-18)
The pentacyclic triterpenes, in particular ursolic acid and oleanolic acid and their derivatives, exist abundantly in the plant kingdom, where they are well known for their anti-inflammatory, antitumour and antimicrobial properties. α-Amyrin and β-amyrin are the precursors of ursolic and
Jianhong Ching et al.
Journal of separation science, 35(1), 53-59 (2011-12-01)
Conventional methods of drug discovery from natural products include bioassay-guided fractionation, which is tedious and has low efficiency. The aim of this work is to develop a platform method to rapidly identify bioactive compounds from crude plant extracts and their

Artigos

Terpenes comprise the largest and most diverse class of secondary metabolites; approximately 55,000 compounds have been identified to date.

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