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Documentos Principais

03880590

Luteolin

primary reference standard

Sinônimo(s):

3′,4′,5,7-Tetrahydroxyflavone

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About This Item

Fórmula empírica (Notação de Hill):
C15H10O6
Número CAS:
Peso molecular:
286.24
Beilstein:
292084
Número CE:
Número MDL:
Código UNSPSC:
85151701
ID de substância PubChem:
NACRES:
NA.24

grau

primary reference standard

prazo de validade

limited shelf life, expiry date on the label

fabricante/nome comercial

HWI

pf

~330 °C (lit.)

aplicação(ões)

food and beverages

cadeia de caracteres SMILES

Oc1cc(O)c2C(=O)C=C(Oc2c1)c3ccc(O)c(O)c3

InChI

1S/C15H10O6/c16-8-4-11(19)15-12(20)6-13(21-14(15)5-8)7-1-2-9(17)10(18)3-7/h1-6,16-19H

chave InChI

IQPNAANSBPBGFQ-UHFFFAOYSA-N

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Descrição geral

Produced and qualified by HWI pharma services GmbH.
Exact content by quantitative NMR can be found on the certificate.

Aplicação

Reference Standard in the analysis of herbal medicinal products

Outras notas

This compound is commonly found in plants of the genus: achillea

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable


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Lien Verschooten et al.
PloS one, 7(10), e48264-e48264 (2012-10-31)
Flavonoids are widely proposed as very interesting compounds with possible chemopreventive and therapeutic capacities. In this study, we showed that in vitro treatment with the flavonoid Luteolin induced caspase-dependent cell death in a model of human cutaneous squamous cell carcinoma
Poyil Pratheeshkumar et al.
PloS one, 7(12), e52279-e52279 (2013-01-10)
Angiogenesis, the formation of new blood vessels from pre-existing vascular beds, is essential for tumor growth, invasion, and metastasis. Luteolin is a common dietary flavonoid found in fruits and vegetables. We studied the antiangiogenic activity of luteolin using in vitro
Theoharis C Theoharides et al.
Advances in experimental medicine and biology, 601, 423-430 (2007-08-24)
Multiple sclerosis (MS) is a demyelinating disease of the central nervous system (CNS) mainly mediated by Th1, but recent evidence indicates that Th2 T cells, mostly associated with allergic reactions, are also involved. Mast cells are involved in allergic and
Yong Lin et al.
Current cancer drug targets, 8(7), 634-646 (2008-11-11)
Luteolin, 3',4',5,7-tetrahydroxyflavone, is a common flavonoid that exists in many types of plants including fruits, vegetables, and medicinal herbs. Plants rich in luteolin have been used in Chinese traditional medicine for treating various diseases such as hypertension, inflammatory disorders, and
Benguo Liu et al.
Food chemistry, 141(2), 900-906 (2013-06-26)
The formation of supramolecular inclusion complexes between luteolin and five cyclodextrins namely β-cyclodextrin (β-CD), methyl-β-cyclodextrin (M-β-CD), hydroxyethyl-β-cyclodextrin (HE-β-CD), hydroxypropyl-β-cyclodextrin (HP-β-CD) and glucosyl-β-cyclodextrin (G-β-CD) was investigated. Results from phase-solubility studies showed that luteolin formed 1:1 stoichiometric inclusion complexes with these cyclodextrins

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