03440

N-Ethyldiisopropylamine

BASF quality, ≥98.0%

• Sinônimo(s): N,N-Diisopropylethylamine, Hünigs base
• Fórmula linear: CH₃CH₂N[CH(CH₃)₂]₂
• Número CAS: 7087-68-5
• Peso molecular: 129.24
• Beilstein: 605301
• Número CE: 230-392-0
• Número MDL: MFCD00008868
• Código UNSPSC: 12352100
• ID de substância PubChem: 329747703
• NACRES: NA.21

Propriedades

• grau: BASF quality
• Nível de qualidade: 200
• Ensaio: ≥98.0%
• Formulário: liquid
• Impurezas: ≤0.5% water
• índice de refração: n20/D 1.414
• p.e.: 126-128 °C (lit.)
• densidade: 0.755 g/mL at 20 °C (lit.); 0.755 g/mL at 20 °C; 0.757 g/mL at 25 °C (lit.)
• grupo funcional: amine
• cadeia de caracteres SMILES: CCN(C(C)C)C(C)C
• InChI: 1S/C8H19N/c1-6-9(7(2)3)8(4)5/h7-8H,6H2,1-5H3
• chave InChI: JGFZNNIVVJXRND-UHFFFAOYSA-N

Descrição

Descrição geral

N,N-Diisopropylethylamine (DIPEA), also known as Hunig′s base, is a sterically hindered amine. It is a non-nucleophilic base commonly employed in substitution reactions, alkylations, and amide couplings, etc. DIPEA is also used as a base in the Pd catalyzed cross-coupling reactions, which include Heck coupling and Sonagashira coupling reactions.

Aplicação

• Catalytic activity in dioxygen reduction: A study utilized Mn complexes with pendent proton donor relays and added base, including N-Ethyldiisopropylamine, to control product selectivity during dioxygen reduction, providing insights into catalytic mechanisms and potential industrial applications (Cook et al., 2024).


• Three-dimensional imaging in medical applications: N-Ethyldiisopropylamine was mentioned in the context of its role in improving the resolution of three-dimensional imaging techniques based on computed tomography angiography (CTA), crucial for preoperative perforator selection in reconstructive surgery (Su et al., 2024).


• Synthesis of Spirocyclopropane-Containing Compounds: Research demonstrated the application of N-Ethyldiisopropylamine in the synthesis of spirocyclopropane-containing 4H-pyrazolo[1,5-a]indoles through alkylative dearomatization and intramolecular N-imination, highlighting its utility in complex organic synthesis (Huang et al., 2023).

Informações de segurança

• Pictogramas: GHS02,GHS06,GHS05,GHS09
• Palavra indicadora: Danger
• Frases de perigo: H225,H302,H318,H331,H335,H411
• Declarações de precaução: P210 - P273 - P280 - P301 + P312 - P304 + P340 + P311 - P305 + P351 + P338
• Classificações de perigo: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Flam. Liq. 2 - STOT SE 3
• Órgãos-alvo: Respiratory system
• Código de classe de armazenamento: 3 - Flammable liquids
• Classe de risco de água (WGK): WGK 2
• Ponto de fulgor (°F): 49.1 °F
• Ponto de fulgor (°C): 9.5 °C
• Equipamento de proteção individual: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter