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24-2109

Sigma-Aldrich

3-Methyl-1-phenyl-2-pyrazoline-5-one

Sinônimo(s):

5-Methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one

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About This Item

Fórmula empírica (Notação de Hill):
C10H10N2O
Número CAS:
89-25-8
Peso molecular:
174.20
Beilstein:
609575
Número CE:
201-891-0
Número MDL:
MFCD00003138
Código UNSPSC:
12352005
ID de substância PubChem:
329752598

forma

solid

disponibilidade

available only in Japan

pb

287 °C/265 mmHg (lit.)

pf

126-128 °C (lit.)

aplicação(ões)

peptide synthesis

cadeia de caracteres SMILES

CC1=NN(C(=O)C1)c2ccccc2

InChI

1S/C10H10N2O/c1-8-7-10(13)12(11-8)9-5-3-2-4-6-9/h2-6H,7H2,1H3

chave InChI

QELUYTUMUWHWMC-UHFFFAOYSA-N

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Adequação

environmental analysis

Pictogramas

Exclamation mark
GHS07

Palavra indicadora

Warning

Frases de perigo

H302,H319

Classificações de perigo

Acute Tox. 4 Oral - Eye Irrit. 2

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 1

Equipamento de proteção individual

dust mask type N95 (US), Eyeshields, Gloves

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Mitsugi Shimoda et al.
World journal of gastroenterology, 18(27), 3520-3526 (2012-07-25)
To investigate the effect of E3-methyl-1-phenyl-2-pyrazolin-5-one (Edr) on hepatic ischemia-reperfusion (I/R) injury and liver regeneration in a porcine hepatectomy model. One hour ischemia was induced by occluding the vessels and the bile duct of the right and median lobes. A
Manabu Ohta et al.
Brain research, 1490, 184-192 (2012-09-18)
Traumatic axonal injury (TAI), a feature of traumatic brain injury (TBI), progressively evolves over hours through impaired axonal transport and is thought to be a major contributor to cognitive dysfunction. In spite of various studies suggesting that pharmacologic or physiologic
Ajmal Ahmad et al.
Molecular and cellular biochemistry, 367(1-2), 215-225 (2012-06-01)
Stroke is a life-threatening disease with major cause of mortality and morbidity worldwide. The neuronal damage following cerebral ischemia is a serious risk to stroke patients. Oxidative stress and apoptotic damage play an important role in cerebral ischemic pathogenesis and
Laura Monturiol-Gross et al.
The Journal of infectious diseases, 206(8), 1218-1226 (2012-08-21)
Clostridium perfringens, the most broadly distributed pathogen in nature, produces a prototype phospholipase C, also called α-toxin, which plays a key role in the pathogenesis of gas gangrene. α-Toxin causes plasma membrane disruption at high concentrations, but the role of
Dongqing Yuan et al.
PloS one, 9(6), e99219-e99219 (2014-06-05)
Edaravone (3-methyl-1-phenyl-2-pyrazolin-5-one), a free radical scavenger, is used for the clinical treatment of retinal injury. In this study, we investigated the protective effects of edaravone against diabetic retinal damage in the mouse. Diabetic retinopathy in the mouse was induced by
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