ATPDS-RO

Adenosine 5′-triphosphate disodium salt trihydrate

=99%, pkg of 1 g (10519979001), pkg of 5 g (10519987001)

• Sinônimo(s): ATP
• Fórmula empírica (Notação de Hill): C₁₀H₂₀N₅Na₂O₁₆P₃
• Número CAS: 51963-61-2
• Peso molecular: 605.19
• Número MDL: MFCD00150754
• Código UNSPSC: 41106305
• ID de substância PubChem: 329773088

Propriedades

• Nível de qualidade: 100
• descrição: Disodium salt
• Ensaio: 99%
• forma: crystals
• peso molecular: 507.2 (ATP); M_r 551.14 (ATP-Na2)
• embalagem: pkg of 1 g (10519979001); pkg of 5 g (10519987001)
• fabricante/nome comercial: Roche
• temperatura de armazenamento: 2-8°C
• cadeia de caracteres SMILES: O.O.O.[Na+].[Na+].Nc1ncnc2n(cnc12)[C@@H]3O[C@H](COP(O)(=O)OP([O-])(=O)OP(O)([O-])=O)[C@@H](O)[C@H]3O
• InChI: 1S/C10H16N5O13P3.2Na.3H2O/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(26-10)1-25-30(21,22)28-31(23,24)27-29(18,19)20;;;;;/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20);;;3*1H2/q;2*+1;;;/p-2/t4-,6-,7-,10-;;;;;/m1...../s1
• chave InChI: MWEQTWJABOLLOS-AZGWGOJFSA-L

Descrição

Descrição geral

The special quality of ATP contains highly purified Adenosine-5′-triphosphate in crystal form.

Aplicação

Adenosine 5′-triphosphate disodium salt trihydrate has been used:

• in analyzing the ATP turnover cycle of microtubule motors
• for activating the NLR family pyrin domain containing 3 (NLRP3) inflammasome to perform in vitro stimulation of bone marrow-derived dendritic cells (BMDCs)
• for in vitro ubiquitination

It is also suitable for the luminometric determination of luciferase (Luc) activity in cell extracts.

Ações bioquímicas/fisiológicas

Adenosine 5′-triphosphate (ATP) is a key energy currency, with high phosphate transfer potential, in all living organisms. ATP participates in several biological processes such as membrane transport, muscle contraction and synthesis, and degradation of biological molecules. It serves as an intracellular and extracellular signaling molecule in certain cellular processes such as cell motility, organ development, neurotransmission, and insulin secretion. Adenosine 5′-triphosphate (ATP) acts as a substrate for proteins of the kinesin superfamily.

Nota de preparo

Storage conditions (working solution): The reconstituted aqueous solution is stable at 2 to 8 °C for one week.

Outras notas

For life science research only. Not for use in diagnostic procedures.

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable