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Key Documents

MAB4343

Sigma-Aldrich

Anti-SOX-2 Antibody

clone 6F1.2, Chemicon®, from mouse

Sinônimo(s):

Anti-ANOP3, Anti-MCOPS3

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About This Item

Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

fonte biológica

mouse

Nível de qualidade

forma do anticorpo

purified immunoglobulin

tipo de produto de anticorpo

primary antibodies

clone

6F1.2, monoclonal

reatividade de espécies

mouse, human

embalagem

antibody small pack of 25 μg

fabricante/nome comercial

Chemicon®

técnica(s)

immunocytochemistry: suitable
immunohistochemistry: suitable
western blot: suitable

entrada

sample type: mouse embryonic stem cell(s)
sample type neural stem cell(s)
sample type: human embryonic stem cell(s)
sample type induced pluripotent stem cell(s)

Isotipo

IgG2b

nº de adesão NCBI

nº de adesão UniProt

Condições de expedição

ambient

temperatura de armazenamento

2-8°C

modificação pós-traducional do alvo

unmodified

Informações sobre genes

human ... SOX2(6657)
mouse ... Sox2(20674)

Descrição geral

Sox-2 plays a key role in embryonic stem cell development, and has been shown to help stem cells maintain pluripotent potential. It has also been shown to be associated with uncommitted dividing stem cell and precursor cells of the developing CNS.

Imunogênio

Recombinant GST Fusion protein.

Aplicação

Anti-SOX-2 Antibody detects level of SOX-2 & has been published & validated for use in IC, IH & WB.
Research Category
Epigenetics & Nuclear Function
Research Sub Category
Transcription Factors

Qualidade

Tested

Descrição-alvo

~34 kDa

forma física

Format: Purified
Purified Immunoglobulin by protein A affinity chromatography and presented as a liquid in 0.02 M phosphate buffer, pH 7.6, with 0.25 M NaCl. Contains 0.1% sodium azide.

Armazenamento e estabilidade

Maintain refrigerated at 2-8°C in undiluted aliquots for up to 12 months.

Outras notas

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Informações legais

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Knockdown of cancer testis antigens modulates neural stem cell marker expression in glioblastoma tumor stem cells.
Low, J; Dowless, M; Shiyanova, T; Rowlinson, S; Ricci-Vitiani, L; de Maria, R; Pallini et al.
Journal of Biomolecular Screening null
Knockdown of ubiquitin ligases in glioblastoma cancer stem cells leads to cell death and differentiation.
Low, J; Blosser, W; Dowless, M; Ricci-Vitiani, L; Pallini, R; de Maria, R; Stancato, L
Journal of Biomolecular Screening null
Jingli Cai et al.
Developmental biology, 251(2), 221-240 (2002-11-19)
Multipotent neural stem cells (NSCs) present in the developing neural tube (E10.5, neuroepithelial cells; NEP) were examined for the expression of candidate stem cell markers, and the expression of these markers was compared with later appearing precursor cells (E14.5) that
Masoumeh Fakhr Taha et al.
BioMed research international, 2014, 941486-941486 (2014-08-26)
The expression pattern of pluripotency markers in adipose tissue-derived stem cells (ADSCs) is a subject of controversy. Moreover, there is no data about the signaling molecules that regulate these markers in ADSCs. In the present study, we studied the roles
High-content imaging-based screening of microenvironment-induced changes to stem cells.
Vega, SL; Liu, E; Patel, PJ; Kulesa, AB; Carlson, AL; Ma, Y; Becker, ML; Moghe, PV
Journal of Biomolecular Screening null

Artigos

Skip weekend feedings. Defined serum-free and feeder-free expansion media for human pluripotent stem cells (ES and iPS cells). See publications and protocols.

The Simplicon™ RNA Reprogramming Technology is a next generation reprogramming system that uses a single synthetic, polycistronic self-replicating RNA strand engineered to mimic cellular RNA to generate human iPS cells.

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