FCMAB198F

Milli-Mark^® Anti-CD54-FITC Antibody, clone 6.5B5

clone 6.5B5, Milli-Mark^®, from mouse

• Sinônimo(s): Intercellular adhesion molecule 1, ICAM-1, Major group rhinovirus receptor
• Código UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.44
• conjugado: FITC conjugate
• application: FACS
• clone: 6.5B5, monoclonal
• reatividade de espécies: human
• técnica(s): flow cytometry: suitable

Propriedades

• fonte biológica: mouse
• Nível de qualidade: 100
• conjugado: FITC conjugate
• forma do anticorpo: purified immunoglobulin
• tipo de produto de anticorpo: primary antibodies
• clone: 6.5B5, monoclonal
• reatividade de espécies: human
• fabricante/nome comercial: Milli-Mark^®
• técnica(s): flow cytometry: suitable
• Isotipo: IgG1κ
• nº de adesão NCBI: NP_000192
• nº de adesão UniProt: P05362
• Condições de expedição: wet ice
• modificação pós-traducional do alvo: unmodified
• Informações sobre genes: human ... ICAM1(3383)

Descrição

Descrição geral

The CD54 antigen is a single chain glycoprotein with a molecular mass of 90 kDa (Springer, 1990). It is the human intercellular adhesion molecule-1 (ICAM-1) belonging to the immunoglobulin supergene family. The ligand for ICAM-1 is LFA-1 (leucocyte function associated-1 protein) (Berendt, 1992). ICAM-1 is widely expressed on many cell types, although the degree of expression by unstimulated resting cells varies. As a cellular activation antigen the expression of ICAM-1 is up-regulated upon cell activation, being induced particularly in response to cytokines such as interleukin-1, tumor necrosis factor, and interferon- (Berendt, 1992; Wellicome, 1990; Thornhill, 1990). ICAM-1 might be a receptor for rhinovirus (Staunton, 1989). In rejecting kidneys the antibody stains all infiltrating cells strongly as well as glomerulus epithelium, endothelium on capillaries, large vessels, and mesangium (Waugh, 1989).

Especificidade

Antibody recognizes Human CD54 antigen.

Imunogênio

TNF-activated human umbilical vein endothelial cells

Aplicação

Milli-Mark Anti-CD54-FITC Antibody, clone 6.5B5 is an antibody against CD54 for use in FC.

Research Category
Inflammation & Immunology

Research Sub Category
Immunoglobulins & Immunology

Qualidade

Evaluated by flow cytometry using human lymphocytes

Descrição-alvo

90 kDa (Springer, 1990)

forma física

Protein A purified

Purified Mouse monoclonal IgG1 conjugated to FITC in 0.05M Tris-HCl buffer with 1% BSA, Sodium Azide at 0.097% at pH 7.2.

Armazenamento e estabilidade

Maintain refrigerated at 2-8°C protected from light in undiluted aliquots for up to 6 months from date of receipt.

Nota de análise

Control
Human Lymphocytes

Informações legais

MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informações de segurança

• Código de classe de armazenamento: 12 - Non Combustible Liquids
• Classe de risco de água (WGK): WGK 2
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable