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Key Documents

AG221

Sigma-Aldrich

Dopamine D2 Receptor, control peptide for AB5084P

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About This Item

Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.42

fonte biológica

human

Nível de qualidade

forma

liquid

fabricante/nome comercial

Chemicon®

concentração

1 mg/mL

técnica(s)

cell based assay: suitable

nº de adesão NCBI

nº de adesão UniProt

Condições de expedição

dry ice

Descrição geral

28 amino acid peptide sequence from the human D2 R within the cytoplasmic loop #3. The 28 amino acid sequence is shared by both the long and short form.

Aplicação

For use in blocking the staining of AB5084P.

Optimal working dilution must be determined by the end user.
Research Category
Neuroscience
Research Sub Category
Neurotransmitters & Receptors

forma física

Liquid in PBS, pH 7.5. No preservative.

Armazenamento e estabilidade

Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.

Informações legais

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Código de classe de armazenamento

12 - Non Combustible Liquids

Classe de risco de água (WGK)

WGK 2

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable


Certificados de análise (COA)

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Hong Wang et al.
The Journal of comparative neurology, 442(4), 392-404 (2002-01-17)
Glutamatergic neurons within the deep layers of the prefrontal cortex and dopaminergic neurons of the substantia nigra pars compacta preferentially terminate in patch-like regions within the caudate putamen nucleus (CPN). Activation of dopamine D2 receptors is known to potently modulate
V A Boundy et al.
Molecular pharmacology, 43(5), 666-676 (1993-05-01)
Multiple subtypes of dopamine receptors with similar properties have been described. Ligands that have been shown to interact with a single subtype of receptor do not yet exist. The use of immunologic methods provides an alternative approach to distinguish receptors
F J Monsma et al.
Nature, 342(6252), 926-929 (1989-12-21)
Dopamine receptor belong to a large class of neurotransmitter and hormone receptors that are linked to their signal transduction pathways through guanine nucleotide binding regulatory proteins (G proteins). Pharmacological, biochemical and physiological criteria have been used to define two subcategories
Production and characterization of a monoclonal antibody to dopamine D2 receptor: comparison with a polyclonal antibody to a different epitope.
Farooqui, S M, et al.
Biochemical and biophysical research communications, 184, 661-667 (1992)
R Dal Toso et al.
The EMBO journal, 8(13), 4025-4034 (1989-12-20)
Cloned human dopamine D2 receptor cDNA was isolated from a pituitary cDNA library and found to encode an additional 29 amino acid residues in the predicted intracellular domain between transmembrane regions 5 and 6 relative to a previously described rat

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