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Merck
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Key Documents

ABS811

Sigma-Aldrich

Anti-FABP7 Antibody

from rabbit, purified by affinity chromatography

Sinônimo(s):

Fatty acid-binding protein, brain, Brain lipid-binding protein, BLBP, Brain-type fatty acid-binding protein, B-FABP, Fatty acid-binding protein 7, Mammary-derived growth inhibitor related, FABP7

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About This Item

Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

fonte biológica

rabbit

Nível de qualidade

forma do anticorpo

affinity isolated antibody

tipo de produto de anticorpo

primary antibodies

clone

polyclonal

purificado por

affinity chromatography

reatividade de espécies

human

técnica(s)

immunohistochemistry: suitable
western blot: suitable

nº de adesão UniProt

Condições de expedição

wet ice

modificação pós-traducional do alvo

unmodified

Informações sobre genes

human ... FABP7(2173)

Descrição geral

FABP7 is a member of the large family of hydrophobic ligand-binding proteins (FABPs). FABP proteins are involved in lipid metabolism, including uptake and intracellular trafficking of fatty acids and retinoids. In addition, they play a role in gene regulation, cell signaling, cell growth and differentiation. Several reports have suggested a possible role for the different FABP proteins in cancer biology, linking their levels with either increasing or decreasing the degree of malignancy. Nine FABPs (FABP1-FABP9) have been identified. FABP7 is a brain-specific protein that is required for the establishment of the radial glial fiber system in the developing brain, a system that is necessary for the migration of immature neurons to establish cortical layers. It is expressed at high levels in the developing central nervous system. FABP7 has also been found in melanocytic lesions and has shown to regulate proliferation and invasion in melanoma cells in vitro, suggesting that it may play a role in cell proliferation and invasion.

Imunogênio

Epitope: Near Center
FABP7 antibody was raised against a 17 amino acid synthetic peptide from near the center of human FABP7.

Aplicação

Immunohistochemistry Analysis (IHC): 5 μg/mL from a representative lot detected FABP7 in human breast tissue.

Research Category
Signaling
Research Sub Category
Developmental Signaling
This Anti-FABP7 Antibody is validated for use in Western Blotting_x000D_ and Immunohistochemistry for the detection of FABP7.

Qualidade

Evaluated by Western Blotting in human breast tissue lysate.

Western Blotting Analysis (WB): 1 μg/mL of this antibody detected FABP7 in human breast tissue lysate.

Descrição-alvo

~24 kDa observed. Uncharacterized bands may be observed in some lysate(s).

Ligação

Replaces: MABS184

forma física

Antigen Affinity Purified
Purified rabbit polyclonal in buffer containing PBS (pH 7.2) with 0.02% sodium azide.

Armazenamento e estabilidade

Stable for 1 year at 2-8°C from date of receipt.

Outras notas

Concentration: Please refer to lot specific datasheet.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de classe de armazenamento

12 - Non Combustible Liquids

Classe de risco de água (WGK)

WGK 2

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable


Certificados de análise (COA)

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Nolwenn Pasquet et al.
Cerebral cortex (New York, N.Y. : 1991), 29(6), 2482-2498 (2018-06-08)
Modifications of neuronal migration during development, including processes that control cortical lamination are associated with functional deficits at adult stage. Here, we report for the first time that the lack of the serine protease tissue-type Plasminogen Activator (tPA), previously characterized

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