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AB4326

Sigma-Aldrich

Anti-ISL-1 Antibody

from rabbit, purified by affinity chromatography

Sinônimo(s):

ISL LIM homeobox 1, ISL1 transcription factor, LIM/homeodomain, ISL1 transcription factor, LIM/homeodomain, (islet-1)

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About This Item

Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

fonte biológica

rabbit

Nível de qualidade

100

forma do anticorpo

affinity isolated antibody

tipo de produto de anticorpo

primary antibodies

clone

polyclonal

purificado por

affinity chromatography

reatividade de espécies

horse, human, mouse

reatividade da espécie (prevista por homologia)

sheep (based on 100% sequence homology), canine (based on 100% sequence homology), rat (based on 100% sequence homology), equine (based on 100% sequence homology), bovine (based on 100% sequence homology)

técnica(s)

immunocytochemistry: suitable
immunohistochemistry: suitable
western blot: suitable

nº de adesão NCBI

NP_002193

nº de adesão UniProt

P61371

Condições de expedição

wet ice

modificação pós-traducional do alvo

unmodified

Informações sobre genes

human ... ISL1(3670)

Descrição geral

Islet-1 (ISL-1) is a transcription factor that plays an important role in the embryogenesis of pancreatic islets of Langerhans. It is expressed in subsets of neurons of the adrenal medulla and dorsal root ganglion, inner nuclear and ganglion cell layers in the retina, the pineal and some regions of the brain. In mouse embryos, a deficiency of this gene fail to undergo neural tube motor neuron differentiation. More recently it has been identified as a marker for a cardiac progenitor cell lineage that is capable of differentiating into all 3 major heart cell types: cardiomyocytes, smooth muscle and endothelial cell lineages.

Especificidade

Predicted to react with most common vertebrate species based on 100% sequence homology.
This antibody recognizes ISL-1.

Imunogênio

Epitope: Internal region of ISL-1.
KLH-conjugated linear peptide corresponding to human ISL-1.

Aplicação

Anti-ISL-1 Antibody is a Rabbit Polyclonal Antibody for detection of ISL-1 also known as ISL LIM homeobox 1, ISL1 transcription factor LIM/homeodomain & has been validated in WB & IHC.
Immunohistochemistry Analysis: A 1:300 dilution from a previous lot detected ISL-1 in mouse pancreas tissue.

Qualidade

Evaluated by Western Blot in K562 cell lysate.

Western Blot Analysis: 0.5 µg/mL of this antibody detected ISL-1 on 10 µg of K562 cell lysate.

Descrição-alvo

~39 kDa

Outras notas

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

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Código de classe de armazenamento

12 - Non Combustible Liquids

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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