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AB9348

Sigma-Aldrich

Anti-Myelin Basic Protein Antibody

Chemicon®, from chicken

Sinônimo(s):

Anti-C76307, Anti-Hmbpr, Anti-R75289, Anti-golli-mbp, Anti-jve, Anti-mld, Anti-shi

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About This Item

Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

fonte biológica

chicken

Nível de qualidade

100

forma do anticorpo

affinity purified immunoglobulin

tipo de produto de anticorpo

primary antibodies

clone

polyclonal

purificado por

affinity chromatography

reatividade de espécies

human, mouse

fabricante/nome comercial

Chemicon®

técnica(s)

immunocytochemistry: suitable
immunohistochemistry: suitable

nº de adesão NCBI

NM_001025081.1
NM_001025090.1
NM_001025092.1
NM_001025094.1
NM_001025098.1
NM_001025100.1
NM_001025101.1
NM_002385.2

nº de adesão UniProt

P02686

Condições de expedição

wet ice

modificação pós-traducional do alvo

unmodified

Informações sobre genes

human ... MBP(4155)
mouse ... Mbp(17196)

Especificidade

Recognizes Myelin Basic Protein (MBP).

Imunogênio

Synthetic peptide from human/mouse MBP.

Aplicação

Anti-Myelin Basic Protein Antibody detects level of Myelin Basic Protein & has been published & validated for use in IC, IH.
Immunohistochemistry: 1:50-1:100 using 2% paraformaldehyde fixed tissues.

Immunocytochemistry: 1:50-1:100 using 2% paraformaldehyde fixed cells.

Optimal working dilutions must be determined by the end user.
Research Category
Neuroscience
Research Sub Category
Neuronal & Glial Markers

Neurochemistry & Neurotrophins

forma física

Affinity purified chicken IgY. Liquid in PBS, pH 7.2 with 0.02% sodium azide.

Armazenamento e estabilidade

Maintain at 2-8°C in undiluted aliquots for up to 6 months after date of receipt. It is recommended that you store the antibody in the dark.

Outras notas

2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research

Informações legais

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de classe de armazenamento

12 - Non Combustible Liquids

Classe de risco de água (WGK)

WGK 2

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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Proceedings of the National Academy of Sciences of the United States of America, 114(33), E6982-E6991 (2017-08-02)
Proinflammatory mononuclear phagocytes (MPs) play a crucial role in the progression of multiple sclerosis (MS) and other neurodegenerative diseases. Despite advances in neuroimaging, there are currently limited available methods enabling noninvasive detection of MPs in vivo. Interestingly, upon activation and
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PloS one, 8(8), e71076-e71076 (2013-08-21)
Although the peripheral nerve is capable of regeneration, only a small minority of patients regain normal function after surgical reconstruction of a major peripheral nerve lesion, resulting in a severe and lasting negative impact on the quality of life. Glial
Bradley A Heller et al.
The Journal of cell biology, 204(7), 1219-1236 (2014-04-02)
The PI 3-kinase (PI 3-K) signaling pathway is essential for Schwann cell myelination. Here we have characterized PI 3-K effectors activated during myelination by probing myelinating cultures and developing nerves with an antibody that recognizes phosphorylated substrates for this pathway.
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Promoting the neuroprotective and repair-inducing effector functions of microglia and macrophages, by means of M2 polarisation or alternative activation, is expected to become a new therapeutic approach for central nervous system (CNS) disorders in which detrimental pro-inflammatory microglia and/or macrophages
The 4.1B cytoskeletal protein regulates the domain organization and sheath thickness of myelinated axons.
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