AB5977
Anti-Musashi-1 Antibody
Chemicon®, from rabbit
Sinônimo(s):
Musashi homolog 1
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About This Item
Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Produtos recomendados
fonte biológica
rabbit
Nível de qualidade
forma do anticorpo
affinity purified immunoglobulin
tipo de produto de anticorpo
primary antibodies
clone
polyclonal
purificado por
affinity chromatography
reatividade de espécies
rodent, mouse, rat, human
fabricante/nome comercial
Chemicon®
técnica(s)
immunocytochemistry: suitable
immunohistochemistry: suitable
western blot: suitable
nº de adesão NCBI
nº de adesão UniProt
Condições de expedição
dry ice
modificação pós-traducional do alvo
unmodified
Informações sobre genes
human ... MSI1(4440)
Descrição geral
In mammals, the Musashi family is important for cell fate determination, playing roles in maintenance of the stem-cell state, differentiation and tumorigenesis. Musashi1 (also known as Msi1), is selectivley expressed in neural progenitor cells, including neural stem cells. Outside the nervous system, Musashi1 is a selective marker for intestinal stem or early lineage cells. Musashi1 interacts with the Notch pathway during asymmetric cell division by binding the 3′ UTR of Numb. Numb is prevented from repressing Notch signaling when Musashi1 is present.
Especificidade
Reactivity with other species has not been confirmed.
Recognizes Musashi-1.
Imunogênio
Synthetic peptide, amino acids 5-21 of Musashi.
Aplicação
Detect Musashi-1 using this Anti-Musashi-1 Antibody validated for use in IC, IH & WB.
Immunohistochemistry:
1:200-1:1,000 dilution from a previous lot was used.
Immunocytochemistry:
1:200-1:1,000 dilution from a previous lot was used.
Western blot:
1:200-1:1,000 using ECL.
Optimal working dilutions must be determined by the end user.
1:200-1:1,000 dilution from a previous lot was used.
Immunocytochemistry:
1:200-1:1,000 dilution from a previous lot was used.
Western blot:
1:200-1:1,000 using ECL.
Optimal working dilutions must be determined by the end user.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Neuronal & Glial Markers
Developmental Neuroscience
RNA Binding Protein (RBP)
Neuronal & Glial Markers
Developmental Neuroscience
RNA Binding Protein (RBP)
Qualidade
Routinely evaluated by Western Blot on Human Placenta lysates.
Western Blot Analysis:
1:1000 dilution of this lot detected Musashi-1 on 10 μg of Human placenta lysates.
Western Blot Analysis:
1:1000 dilution of this lot detected Musashi-1 on 10 μg of Human placenta lysates.
Descrição-alvo
39 kDa
Ligação
Replaces: 03-114; 04-1041
forma física
ImmunoAffinity Purified
Purified rabbit polyclonal in buffer containing a solution of 50% saturated ammonium sulfate and PBS containing no preservatives.
Armazenamento e estabilidade
Stable for 1 year at -80ºC from date of receipt.
Nota de análise
Control
Mouse cortical neural stem cells (Catalog No. SCR029).
Mouse cortical neural stem cells (Catalog No. SCR029).
Informações legais
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Exoneração de responsabilidade
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Código de classe de armazenamento
12 - Non Combustible Liquids
Classe de risco de água (WGK)
WGK 2
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
Certificados de análise (COA)
Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.
Já possui este produto?
Encontre a documentação dos produtos que você adquiriu recentemente na biblioteca de documentos.
Long-term proliferation of human embryonic stem cell-derived neuroepithelial cells using defined adherent culture conditions
Shin, Soojung, et al.
Stem Cells, 24, 125-138 (2006)
Cell lineage identification and stem cell culture in a porcine model for the study of intestinal epithelial regeneration.
Gonzalez, LM; Williamson, I; Piedrahita, JA; Blikslager, AT; Magness, ST
Testing null
Neural stem cell detection, characterization, and age-related changes in the subventricular zone of mice
Maslov, Alexander Y, et al.
The Journal of Neuroscience, 24, 1726-1733 (2004)
Postnatal epithelial growth of the small intestine in the rat occurs by both crypt fission and crypt hyperplasia.
Adrian G Cummins, Ben J Jones, Fiona M Thompson
Digestive Diseases and Sciences null
Raffaella Scardigli et al.
Stem cells (Dayton, Ohio), 32(9), 2516-2528 (2014-05-09)
Adult neurogenesis is a multistep process regulated by several extrinsic factors, including neurotrophins. Among them, little is known about the role of nerve growth factor (NGF) in the neurogenic niches of the mouse. Here we analyzed the biology of adult
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