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AB1871

Sigma-Aldrich

Anti-Caspase 1 Antibody

Chemicon®, from rabbit

Sinônimo(s):

ICE

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About This Item

Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

fonte biológica

rabbit

forma do anticorpo

affinity purified immunoglobulin

tipo de produto de anticorpo

primary antibodies

clone

polyclonal

purificado por

affinity chromatography

reatividade de espécies

human, rat, mouse

fabricante/nome comercial

Chemicon®

técnica(s)

immunofluorescence: suitable
immunoprecipitation (IP): suitable
western blot: suitable

nº de adesão NCBI

NM_001223.3
NM_033292.2
NM_033293.2
NM_033294.2
NM_033295.2

nº de adesão UniProt

P29466

Condições de expedição

wet ice

modificação pós-traducional do alvo

unmodified

Informações sobre genes

human ... CASP1(834)
mouse ... Casp1(12362)
rat ... Casp1(25166)

Descrição geral

Caspase-1 (ICE, interleukin-1b-converting enzyme) is the mammalian caspase responsible for the proteolytic conversion of the proforms of interleukin-1b and IL-18 into active cytokines. Like other caspases, caspase-1 itself is synthesized as a proenzyme that is cleaved during activation into large (20 kDa) and small (10 kDa) subunits.

Especificidade

AB1871 recognizes the 45 kDa procaspase-1 as well as the 20 kDa cleaved caspase-1.

Aplicação

This Anti-Caspase 1 Antibody is validated for use in IF, IP, WB for the detection of Caspase 1.
Western blot: 1-4 μg/mL

Immunoprecipitation: 4-8 μg/mL

Immunofluorescence: 10-20 μg/mL

Optimal working dilutions must be determined by end user.

forma física

Affinity purified immunoglobulin. Liquid in PBS, pH 7.2, containing 50% glycerol, 1% BSA and 0.02% sodium azide.

Outras notas

2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research

Informações legais

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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Código de classe de armazenamento

10 - Combustible liquids

Classe de risco de água (WGK)

WGK 2

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