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AB1572

Sigma-Aldrich

Anti-GABA Transporter-2 Antibody

Chemicon®, from rabbit

Sinônimo(s):

GAT-2

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About This Item

Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

fonte biológica

rabbit

Nível de qualidade

100

forma do anticorpo

affinity isolated antibody

tipo de produto de anticorpo

primary antibodies

clone

polyclonal

purificado por

affinity chromatography

reatividade de espécies

mouse, rat

fabricante/nome comercial

Chemicon®

técnica(s)

immunohistochemistry: suitable
western blot: suitable

nº de adesão NCBI

NM_016615.2

nº de adesão UniProt

Q9NSD5

Condições de expedição

wet ice

modificação pós-traducional do alvo

unmodified

Informações sobre genes

mouse ... Slc6A13(14412)
rat ... Slc6A13(171163)

Especificidade

GABA Transporter-2 (GAT-2), C-terminus. No cross-reactivity to the C-termini of other transmitter transporters detected.

Imunogênio

GAT-2, C-terminus (aa 593-602)

Aplicação

Immunohistochemistry: 1:500-1:750 on 4% paraformaldehyde fixed tissue.

It is recommended that the antibody is diluted in PBS containing 10% normal goat serum and 0.5% Triton X-100. AB1572 has been used for light microscopic studies of the rat nervous system.

Western blot: It has been reported that this antibody works for Western blot (Conti, 1999).

Optimal working dilutions must be determined by the end user.
Research Category
Neuroscience
Research Sub Category
Ion Channels & Transporters
This Anti-GABA Transporter-2 Antibody is validated for use in IH, WB for the detection of GABA Transporter-2.

forma física

Affinity purified antibody. Purified in PBS with 0.1% sodium azide.

Armazenamento e estabilidade

Maintain lyophilized material at 2-8°C for up to 12 months. Maintain reconstituted material at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.

Outras notas

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Informações legais

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Pictogramas

Exclamation mark
GHS07

Palavra indicadora

Warning

Frases de perigo

H302 + H312 + H332,H412

Classificações de perigo

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3

Código de classe de armazenamento

13 - Non Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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Hong Lin et al.
Disease models & mechanisms, 10(12), 1529-1538 (2017-12-21)
Friedreich ataxia (FRDA) is an autosomal recessive neurodegenerative disorder with progressive ataxia that affects both the peripheral and central nervous system (CNS). While later CNS neuropathology involves loss of large principal neurons and glutamatergic and GABAergic synaptic terminals in the
Maria Elisa Calcagnotto et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 22(17), 7596-7605 (2002-08-28)
Children with brain malformations often exhibit an intractable form of epilepsy. Although alterations in cellular physiology and abnormal histology associated with brain malformations has been studied extensively, synaptic function in malformed brain regions remains poorly understood. We used an animal
J Johnson et al.
The Journal of comparative neurology, 375(2), 212-224 (1996-11-11)
gamma-Aminobutyric acid (GABA) plasma membrane transporters (GATs) influence synaptic neurotransmission by high-affinity uptake and release of GABA. The distribution and cellular localization of GAT-1, GAT-2, and GAT-3 in the rat retina have been evaluated by using affinity-purified polyclonal antibodies directed

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