8.20112

Anthranilic acid

for synthesis

• Sinônimo(s): Anthranilic acid, 2-Aminobenzoic acid
• Fórmula linear: 2-(NH₂)C₆H₄COOH
• Número CAS: 118-92-3
• Peso molecular: 137.14
• Número MDL: MFCD00007712
• Código UNSPSC: 12352106
• Número do índice EC: 204-287-5
• NACRES: NA.22

Propriedades

• pressão de vapor: 0.001 hPa ( 52.6 °C)
• Nível de qualidade: 200
• Ensaio: ≥99.0% (acidimetric)
• Formulário: solid
• temperatura de autoignição: >530 °C
• potência: 4550 mg/kg LD₅₀, oral (Rat)
• pf: 146-148 °C
• temperatura de transição: flash point 150 °C
• solubilidade: 4.5 g/L
• densidade: 1.383 g/cm³ at 23 °C
• densidade volumétrica: 500 kg/m³
• temperatura de armazenamento: 2-30°C
• InChI: 1S/C7H7NO2/c8-6-4-2-1-3-5(6)7(9)10/h1-4H,8H2,(H,9,10)
• chave InChI: RWZYAGGXGHYGMB-UHFFFAOYSA-N

Descrição

Aplicação

• Anthranilic acid in bio-imaging: Anthranilic acid produced by Virgibacillus salarius MML1918 was characterized for its potential in bio-imaging applications, demonstrating utility in visualizing biological processes (Nandhagopal and Narayanasamy, 2024).


• Anthranilic acid as a metabolite biomarker: A study utilized targeted metabolomics to identify anthranilic acid as a biomarker in Salmonella enteritidis-contaminated chickens, enhancing detection and safety measures in food chemistry (Chen et al., 2023).


• Anthranilic acid in metabolic pathway analysis: A comparative study on the kynurenine pathway in cell lines incorporated anthranilic acid, utilizing LC-MS/MS-based targeted metabolomics to explore selective inhibition of indoleamine and tryptophan 2,3-dioxygenases (Villani et al., 2024).


• Anthranilic acid in quantitative metabolomics: Liquid chromatography-tandem mass spectrometry was used for the simultaneous quantification of tryptophan, serotonin, and kynurenine pathway metabolites, including anthranilic acid, in various biological samples, aiding in comprehensive metabolic profiling (Frobel et al., 2023).

Nota de análise

Assay (acidimetric): ≥ 99.0 %
Melting range (lower value): ≥ 144 °C
Melting range (upper value): ≤ 147 °C
Identity (IR): passes test

Informações de segurança

• Pictogramas: GHS05
• Palavra indicadora: Danger
• Frases de perigo: H318
• Declarações de precaução: P280 - P305 + P351 + P338
• Classificações de perigo: Eye Dam. 1
• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): 302.0 °F - closed cup
• Ponto de fulgor (°C): 150 °C - closed cup