Pular para o conteúdo
Merck
Todas as fotos(2)

Key Documents

View All Documentation

444968

Sigma-Aldrich

PD0325901

≥95% (HPLC), liquid, MEK1/2 inhibitor, Calbiochem®

Sinônimo(s):

InSolution MEK1/2 Inhibitor III, PD0325901, PD 0325901, N-((2R)-2,3-Dihyroxypropoxy)-3,4-difluoro-2-((2-fluoro-4-iodophenyl)amino)-benzamide, PD325901

Faça loginpara ver os preços organizacionais e de contrato
Todas as fotos(2)

About This Item

Fórmula empírica (Notação de Hill):
C16H14F3IN2O4
Número CAS:
391210-10-9
Peso molecular:
482.19
Número MDL:
MFCD08435926
Código UNSPSC:
12352200
NACRES:
NA.77

product name

MEK1/2 Inhibitor III, PD0325901, InSolution, ≥95%

Nível de qualidade

100

Ensaio

≥95% (HPLC)

forma

liquid

fabricante/nome comercial

Calbiochem®

condição de armazenamento

OK to freeze
desiccated (hygroscopic)
protect from light

Condições de expedição

ambient

temperatura de armazenamento

−20°C

InChI

1S/C16H14F3IN2O4/c17-11-3-2-10(16(25)22-26-7-9(24)6-23)15(14(11)19)21-13-4-1-8(20)5-12(13)18/h1-5,9,21,23-24H,6-7H2,(H,22,25)/t9-/m1/s1

chave InChI

SUDAHWBOROXANE-SECBINFHSA-N

Embalagem

Packaged under inert gas

Advertência

Toxicity: Regulatory Review (Z)

forma física

A 50 mM (5 mg/207 µl) solution of MEK1/2 Inhibitor III, PD0325901 (Cat. No. 444966) in DMSO.

Informações legais

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Código de classe de armazenamento

10 - Combustible liquids

Classe de risco de água (WGK)

WGK 2

Ponto de fulgor (°F)

188.6 °F - closed cup - (refers to pure substance)

Ponto de fulgor (°C)

87 °C - closed cup - (refers to pure substance)

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

Já possui este produto?

Encontre a documentação dos produtos que você adquiriu recentemente na biblioteca de documentos.

Visite a Biblioteca de Documentos

Zhao Yang et al.
Journal of biochemical and molecular toxicology, 36(12), e23219-e23219 (2022-09-20)
Polyphyllin I (PPI) is a famous traditional medicine ingredient, which has been explored in wide range of areas. Nevertheless, whether PPI exerts any functions in coronary artery disease (CAD) is still uncertified. Herein, we probed the effect and mechanism of
Gayan I Balasooriya et al.
Nature communications, 13(1), 5984-5984 (2022-10-11)
Each mammalian autosomal gene is represented by two alleles in diploid cells. To our knowledge, no insights have been made in regard to allele-specific regulatory mechanisms of autosomes. Here we use allele-specific single cell transcriptomic analysis to elucidate the establishment
Shihai Zhang et al.
PLoS genetics, 17(10), e1009832-e1009832 (2021-10-22)
The mammalian target of rapamycin complex 1 (mTORC1) senses multiple stimuli to regulate anabolic and catabolic processes. mTORC1 is typically hyperactivated in multiple human diseases such as cancer and type 2 diabetes. Extensive research has focused on signaling pathways that
Jenny F Nathans et al.
Science advances, 7(3) (2021-02-02)
The G1-S checkpoint is thought to prevent cells with damaged DNA from entering S phase and replicating their DNA and efficiently arrests cells at the G1-S transition. Here, using time-lapse imaging and single-cell tracking, we instead find that DNA damage
Aurélia Huyghe et al.
Nature cell biology, 22(4), 389-400 (2020-04-02)
In mouse embryonic stem cells (mESCs), chemical blockade of Gsk3α/β and Mek1/2 (2i) instructs a self-renewing ground state whose endogenous inducers are unknown. Here we show that the axon guidance cue Netrin-1 promotes naive pluripotency by triggering profound signalling, transcriptomic

Nossa equipe de cientistas tem experiência em todas as áreas de pesquisa, incluindo Life Sciences, ciência de materiais, síntese química, cromatografia, química analítica e muitas outras.

Entre em contato com a assistência técnica