440153

L-α-lysophosphatidylinositol sodium salt

>99% (HPLC), powder, GPR55 agonist, Calbiochem^®

• Sinônimo(s): L-α-lysophosphatidylinositol Sodium Salt, Soy, L-α-lysophosphatidylinositol LPI, Lyso PI, Soy Lyso PI
• Fórmula empírica (Notação de Hill): C₂₅H₄₈NaO₁₂P
• Número CAS: 796963-91-2
• Peso molecular: 594.61
• Código UNSPSC: 12352200
• NACRES: NA.77

Propriedades

• product name: L-α-lysophosphatidylinositol Sodium Salt, Soy, A potent agonist and assumed endogenous ligand of GPR55.
• Nível de qualidade: 100
• Ensaio: >99% (HPLC)
• forma: powder
• fabricante/nome comercial: Calbiochem^®
• condição de armazenamento: OK to freeze; desiccated (hygroscopic); protect from light
• cor: white
• solubilidade: DMSO: soluble
• Condições de expedição: ambient
• temperatura de armazenamento: −20°C
• cadeia de caracteres SMILES: O[C@H]1[C@H](OP(OC[C@H](O)COC(CCCCCCCCCCCCCCC)=O)([O-][Na+])=O)[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O

Descrição

Descrição geral

A potent agonist and assumed endogenous ligand of GPR55, shown to induce rapid phosphorylation of p38 mitogen-activated protein kinase (MAPK) and its downstream activating transcription factor 2 (ATF2) in both GPR55-transfected HEK293 cells, and in IM-9 lymphoblastoid cells naturally expressing GPR55 at 1 µM, while having no effect on vector-transfected cells. In addition, shown to enhance serum induced cell migration in MCF-7 cells over expressing GPR55.

A potent agonist and assumed endogenous ligand of GPR55, shown to induce rapid phosphorylation of p38 mitogen-activated protein kinase (MAPK) and its downstream activating transcription factor 2 (ATF2) in both GPR55-transfected HEK293 cells, and in IM-9 lymphoblastoid cells naturally expressing GPR55 at 1uM, while having no effect on vector-transfected cells. In addition, shown to enhance serum induced cell migration in MCF-7 cells over expressing GPR55.

Embalagem

Packaged under inert gas

Advertência

Toxicity: Standard Handling (A)

Outras notas

Oka, S., et al. 2010. J Biochem.147, 671.
Oka, S., et al. 2007.
Biochem. Biophys. Res. Commun.362, 928.

Informações legais

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 2
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable