850102P

16:0 Lyso PI

1-palmitoyl-2-hydroxy-sn-glycero-3-phosphoinositol (ammonium salt), powder

• Sinônimo(s): 1-hexadecanoyl-2-hydroxy-sn-glycero-3-phospho-(1′-myo-inositol) (ammonium salt); PI(16:0/0:0; 110717
• Fórmula empírica (Notação de Hill): C₂₅H₅₂NO₁₂P
• Número CAS: 141553-69-7
• Peso molecular: 589.65
• Código UNSPSC: 51191904
• NACRES: NA.25

Propriedades

• Ensaio: >99% (LPI; may contain up to 10% of the 2-LPI isomer, TLC)
• Formulário: powder
• embalagem: pkg of 1 × 100 μg (with stopper and crimp cap (850102P-100ug)); pkg of 1 × 500 μg (with stopper and crimp cap (850102P-500ug))
• fabricante/nome comercial: Avanti Research^™ - A Croda Brand 850102P
• tipo de lipídio: phosphoglycerides
• Condições de expedição: dry ice
• temperatura de armazenamento: −20°C
• cadeia de caracteres SMILES: [H][C@@](COP([O-])(O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](O)[C@H]1O)=O)(O)COC(CCCCCCCCCCCCCCC)=O.[NH4+]

Descrição

Descrição geral

Lysophosphatidylinositol (LPI) is a bioactive lipid.

Aplicação

16:0 Lyso PI (1-palmitoyl-2-hydroxy-sn-glycero-3-phosphoinositol) has been used as a lipid standard in the optimization of the liquid chromatography–mass spectrometry (LC-MS) method conditions and also has been used as lysophosphatidylinositol (LPI) substrates in lysophosphatidylinositol acyltransferase biochemical assay to assay lyso-phosphatidylinositol acyltransferase (LPIAT) activity of liver microsomes. It may also be used as synthetic LPI to compare its effect with LPI from liver in transferrin (Tf)mediated endocytosis.

Ações bioquímicas/fisiológicas

Increased circulating levels of L-alpha-lysophosphatidylinositol (LPI) are associated with cancer and LPI is a potent ligand for the G-protein-coupled receptor GPR55.

Lysophosphatidylinositol (LPI) has the ability to modulate cancer cell migration. It can control the functions of endothelium. LPI can serve as an autocrine regulator of cell growth, hence its known to participate in cancer progression. It can stimulate signaling cascades, that are essential for survival, migration and proliferation of cells.

Embalagem

2 mL Amber Serum Vial with Stopper and Crimp Cap (850102P-100ug)

2 mL Amber Serum Vial with Stopper and Crimp Cap (850102P-500ug)

Informações legais

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): No data available
• Ponto de fulgor (°C): No data available