14-720-M

FAK Protein, active, 10 µg

Active, N-terminal 6His-tagged, recombinant, human FAK, amino acids 411-686, for use in Kinase Assays.

• Código UNSPSC: 12352202
• eCl@ss: 32160405
• NACRES: NA.32

Propriedades

• fonte biológica: human
• Nível de qualidade: 100
• recombinante: expressed in baculovirus infected Sf21 cells
• linha de produto: Upstate^®
• atividade específica: (For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.)
• peso molecular: M_w 35.5 kDa
• purificado por: (Ni²⁺/NTA-agarose)
• reatividade de espécies: human
• fabricante/nome comercial: Upstate^®
• técnica(s): activity assay: suitable (kinase)
• nº de adesão: (FUNCTION: SwissProt: Q05397 # Non-receptor protein-tyrosine kinase implicated in signaling pathways involved in cell motility, proliferation and apoptosis. Activated by tyrosine-phosphorylation in response to either integrin clustering induced by cell adhesion or antibody cross-linking, or via G-protein coupled receptor (GPCR) occupancy by ligands such as bombesin or lysophosphatidic acid, or via LDL receptor occupancy. Plays a potential role in oncogenic transformations resulting in increased kinase activity. ); NM_005607.3
• nº de adesão NCBI: NM_005607.3; NM_153831.2
• nº de adesão UniProt: Q05397
• doença(s) relevante(s): obesity; metabolic disorders
• Informações sobre genes: human ... PTK2(5747)

Descrição

Descrição geral

N-terminal 6His-tagged, recombinant, human FAK, amino acids 411-686

Ações bioquímicas/fisiológicas

Protein Target: FAK

Embalagem

Also available in 10 μg size and in bulk

Qualidade

routinely evaluated by phosphorylation of 100μM substrate peptide (EEEEYEEEEEEYYIIEEEEEEYEEEEEEYYEEEEEEKKK)

Descrição-alvo

FAK

Outras notas

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

Informações legais

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informações de segurança

• Pictogramas: GHS07
• Palavra indicadora: Warning
• Frases de perigo: H317
• Declarações de precaução: P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364
• Classificações de perigo: Skin Sens. 1
• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°C): Not applicable