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Key Documents

07-909

Sigma-Aldrich

Anti-phospho-Src (Tyr418) Antibody

Upstate®, from rabbit

Sinônimo(s):

c-Src, p60-Src Src kinase

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About This Item

Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

fonte biológica

rabbit

Nível de qualidade

100

forma do anticorpo

affinity purified immunoglobulin

tipo de produto de anticorpo

primary antibodies

clone

polyclonal

purificado por

affinity chromatography

reatividade de espécies

chicken, human, mouse

fabricante/nome comercial

Upstate®

técnica(s)

immunocytochemistry: suitable
immunohistochemistry: suitable
western blot: suitable

Isotipo

IgG

nº de adesão NCBI

NM_005417.3
NM_198291.1

nº de adesão UniProt

P12931

Condições de expedição

dry ice

modificação pós-traducional do alvo

phosphorylation (pTyr418)

Informações sobre genes

human ... SRC(6714)

Especificidade

Predicted to cross-react with Rat and Frog (100% homologous) based on sequence homology.
Recognizes Src phosphorylated on Tyrosine residue 418.

Imunogênio

Peptide corresponding to amino acid region encompassing the human, mouse, rat, chicken, and frog phospho-Src (Tyr418)

Aplicação

Anti-phospho-Src (Tyr418) Antibody detects level of phospho-Src (Tyr418) & has been published & validated for use in IC, IH & WB.
Immunoblot Analysis: 1:1000 dilutions of this lot detected phospho-Src (Tyr418) in RIPA lysate of Src transfected CEF cells.
Research Category
Signaling
Research Sub Category
Cytoskeletal Signaling

Qualidade

Routinely evaluated by immunoblot.

Descrição-alvo

60 kDa

forma física

Affinity Purified rabbit polyclonal IgG in PBS (without Mg2+ and Ca2+), pH 7.3 containing 0.5 mg/mL BSA (IgG, protease free) and 0.025% sodium azide and 50% glycerol.
ImmunoAffinity Purified

Armazenamento e estabilidade

Maintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Nota de análise

Control
Chick embryo fibroblast (CEF) cells expressing human wild-type Src protein

Outras notas

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Informações legais

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de classe de armazenamento

12 - Non Combustible Liquids

Classe de risco de água (WGK)

WGK 2

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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Applied Biochemistry and Biotechnology null
Src: regulation, role in human carcinogenesis and pharmacological inhibitors.
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Altered redox state has been related to the development of normal pregnancy (NP) and preeclampsia (PE). Endothelial KCa2.3 and KCa3.1 (KCas) play an important role in vasodilation, and KCas levels are affected by oxidative stress. We investigated the mechanisms of
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