SAB4504536

Anti-phospho-Src (pTyr⁴¹⁸) antibody produced in rabbit

affinity isolated antibody

• Sinônimo(s): Anti-ASV, Anti-SRC1, Anti-THC6, Anti-c-SRC, Anti-p60-Src
• Código UNSPSC: 12352203
• NACRES: NA.41

Propriedades

• fonte biológica: rabbit
• conjugado: unconjugated
• forma do anticorpo: affinity isolated antibody
• tipo de produto de anticorpo: primary antibodies
• clone: polyclonal
• forma: buffered aqueous solution
• peso molecular: antigen 59 kDa
• reatividade de espécies: human, mouse, rat
• concentração: ~1 mg/mL
• técnica(s): ELISA: 1:20000; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• nº de adesão NCBI: P12931
• nº de adesão UniProt: P12931
• Condições de expedição: wet ice
• temperatura de armazenamento: −20°C
• modificação pós-traducional do alvo: phosphorylation (pTyr418)
• Informações sobre genes: human ... SRC(6714)

Descrição

Descrição geral

SRC (proto-oncogene, non-receptor tyrosine kinase) belongs to the Src family kinases (SFKs). It contains an amino-terminal domain, conserved Src-homology domains (SH2 and SH3), a tyrosine kinase domain and the carboxyl-terminus. This gene is located on human chromosome 20q11.

Imunogênio

The antiserum was produced against synthesized peptide derived from human Src around the phosphorylation site of Tyr418.

Immunogen Range: 386-435

Aplicação

Anti-phospho-Src (pTyr418) antibody has been used in immunofluorescence.

Ações bioquímicas/fisiológicas

SRC (proto-oncogene, non-receptor tyrosine kinase) controls early HIV-1 (human immunodeficiency virus 1) infection post-entry. This gene participates in fundamental physiological and pathological processes like carcinogenesis and tumor progression. Src kinase activity helps in the migration of endothelial cells.

Características e benefícios

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forma física

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable