07-412
Anti-dimethyl-Arginine Antibody, symmetric (SYM10)
serum, Upstate®
Sinônimo(s):
Anti-SYM10, Dimethyl-Arginine Detection Ab, Symmetric Dimethyl-Arginine Ab
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About This Item
Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Produtos recomendados
fonte biológica
rabbit
Nível de qualidade
forma do anticorpo
serum
tipo de produto de anticorpo
primary antibodies
clone
polyclonal
reatividade de espécies
mouse, human
fabricante/nome comercial
Upstate®
técnica(s)
immunocytochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable
Isotipo
IgG
Condições de expedição
dry ice
modificação pós-traducional do alvo
dimethylation (Arg)
Descrição geral
Arginine methylation is a post-translational modification that results in the formation of asymmetrical and symmetrical dimethylated arginines (a- and sDMA).
Does not recognize non-methylated peptides, peptides containing asymmetrically dimethylated arginines, or a peptide containing a single symmetric dimethylarginine.
Especificidade
Recognizes proteins that contain multiple symmetrically dimethylated arginines, including p80-Coilin and the Sm protein B, B′ and D.
Imunogênio
peptide containing four symmetrical dimethyl-arginine-glycine repeats
Aplicação
Anti-dimethyl-Arginine Antibody, symmetric (SYM10) is a high quality Rabbit Polyclonal Antibody for the detection of dimethyl-Arginine & has been validated in ICC, IP & WB.
Research Category
Signaling
Signaling
Research Sub Category
Chromatin Biology
Chromatin Biology
Qualidade
routinely evaluated by immunoblot in RIPA lysates from Jurkat cells
Descrição-alvo
varies
forma física
Whole rabbit antiserum containing 0.05% sodium azide and 30% glycerol. Liquid at -20°C.
Armazenamento e estabilidade
Maintain for 1 year at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Nota de análise
Control
Positive Antigen Control: Catalog #12-303, Jurkat cell lysate.
Positive Antigen Control: Catalog #12-303, Jurkat cell lysate.
Outras notas
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Informações legais
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Exoneração de responsabilidade
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Código de classe de armazenamento
12 - Non Combustible Liquids
Classe de risco de água (WGK)
WGK 1
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
Certificados de análise (COA)
Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.
Já possui este produto?
Encontre a documentação dos produtos que você adquiriu recentemente na biblioteca de documentos.
He Liu et al.
Cell death & disease, 13(4), 299-299 (2022-04-06)
A high plasma level of the choline-derived metabolite trimethylamine N-oxide (TMAO) is closely related to the development of cardiovascular disease. However, the underlying mechanism remains unclear. In the present study, we demonstrated that a positive correlation of protein arginine methyltransferase
Xiaodi Xu et al.
Journal of fungi (Basel, Switzerland), 7(10) (2021-10-24)
Penicillium expansum is one of the most common and destructive post-harvest fungal pathogens that can cause blue mold rot and produce mycotoxins in fruit, leading to significant post-harvest loss and food safety concerns. Arginine methylation by protein arginine methyltransferases (PRMTs)
Arginine methylation mediated by the Arabidopsis homolog of PRMT5 is essential for proper pre-mRNA splicing.
Deng, X; Gu, L; Liu, C; Lu, T; Lu, F; Lu, Z; Cui, P; Pei, Y; Wang, B; Hu, S; Cao, X
Proceedings of the National Academy of Sciences of the USA null
Lindsay M Webb et al.
Frontiers in immunology, 10, 524-524 (2019-04-04)
Multiple sclerosis is an autoimmune disease of the central nervous system (CNS) mediated by CD4+ T cells and modeled via experimental autoimmune encephalomyelitis (EAE). Inhibition of PRMT5, the major Type II arginine methyltransferase, suppresses pathogenic T cell responses and EAE.
Joris Paris et al.
Retrovirology, 15(1), 48-48 (2018-07-13)
Nuclear localization of Gag is a property shared by many retroviruses and retrotransposons. The importance of this stage for retroviral replication is still unknown, but studies on the Rous Sarcoma virus indicate that Gag might select the viral RNA genome
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