09-814
Anti-dimethyl-Arginine Antibody, asymmetric (ASYM25)
serum, from rabbit
Sinônimo(s):
dimethyl-arginine, asymmetric
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About This Item
Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Produtos recomendados
fonte biológica
rabbit
Nível de qualidade
forma do anticorpo
serum
tipo de produto de anticorpo
primary antibodies
clone
polyclonal
reatividade de espécies
mouse
reatividade da espécie (prevista por homologia)
rat (based on 100% sequence homology), human (based on 100% sequence homology)
técnica(s)
western blot: suitable
Condições de expedição
wet ice
modificação pós-traducional do alvo
unmodified
Descrição geral
Asymmetrical dimethlarginine (ADMA) is an endogenous, L-arginine metabolite arising from the proteolysis of methylated arginine containing proteins and is a known inhibitor of nitric oxide synthase (NOS). In various studies, ADMA has been observed as having a regulatory role in cell motility and the actin cytoskeleton. Elevated levels of ADMA are associated with sporadic FSGS, coronary artery disease, hypertension, peripheral arterial occlusive disease, obesity, stroke, preeclampsia, and cardiovascular mortality/morbidity in patients with diabetic nephropathy.
Especificidade
This antibody recognizes dimethylated arginines.
Imunogênio
KLH-conjugated linear peptide containing asymmetric dimethyl-arginine-glycine repeats.
Aplicação
Detect dimethyl-Arginine using this Anti-dimethyl-Arginine Antibody, asymmetric (ASYM25) validated for use in WB.
Qualidade
Evaluated by Western Blot in PRMT1 treated and untreated MEF cell lysates.
Western Blot Analysis: 1:1,000 dilution of this antibody detected dimethyl-Arginine on 10 µg of PRMT1 treated and untreated MEF cell lysates.
Western Blot Analysis: 1:1,000 dilution of this antibody detected dimethyl-Arginine on 10 µg of PRMT1 treated and untreated MEF cell lysates.
Descrição-alvo
Multiple. This antibody detects proteins containing asymmetrical dimethylated arginines.
Nota de análise
Control
PRMT1 treated and untreated MEF cell lysates
PRMT1 treated and untreated MEF cell lysates
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Código de classe de armazenamento
10 - Combustible liquids
Classe de risco de água (WGK)
WGK 1
Certificados de análise (COA)
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