07-1213

Anti-IP3 Receptor 1 Antibody

serum, from rabbit

• Sinônimo(s): IP3 receptor isoform 1, Type 1 InsP3 receptor, Type 1 inositol 1,4,5-trisphosphate receptor, inositol 1,4,5-triphosphate receptor, type 1, spinocerebellar ataxia 15, spinocerebellar ataxia 16
• Código UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Propriedades

• fonte biológica: rabbit
• Nível de qualidade: 100
• forma do anticorpo: serum
• tipo de produto de anticorpo: primary antibodies
• clone: polyclonal
• reatividade de espécies: mouse, human
• reatividade da espécie (prevista por homologia): canine, rat
• técnica(s): immunohistochemistry: suitable (paraffin); western blot: suitable
• Isotipo: IgG
• nº de adesão UniProt: Q14643
• Condições de expedição: wet ice
• modificação pós-traducional do alvo: unmodified
• Informações sobre genes: dog ... Itpr1(476548) ; human ... ITPR1(3708) ; mouse ... Itpr1(16438) ; rat ... Itpr1(25262)

Descrição

Descrição geral

IP3 Receptor 1 is an intracellular channel that when stimulated by inositol 1,4,5-triphosphate mediates the release of calcium from the endoplasmic reticulum. Defects within the gene ITPR1 cause a group of cerebellar disorders known as spinocerebellar ataxia type 15 (SCA15). This receptor is widely expressed in tissue.

Especificidade

The antibody reacts with the 300 kDa IP3 Receptor 1 protein.

Imunogênio

Synthetic peptide from the N-terminal of human IP3 Receptor 1.

Aplicação

Immunohistochemistry Analysis: A 1:100 dilution of this antibody detected IP3 Receptor 1 in mouse cerebellum tissue.

Research Category
Signaling

Research Sub Category
Lipid Signaling

This Anti-IP3 Receptor 1 Antibody is validated for use in IH(P), WB for the detection of IP3 Receptor 1.

Qualidade

Evaluated by Western Blot in C2C12 cell lysates.
Western Blot Analysis: 1:500 dilution of this lot detected IP3 RECPT 1 on 10 ug of C2C12 lysates.

Descrição-alvo

Approx. 300 kDa

Ligação

Replaces: AB9072

forma física

Rabbit serum. Liquid

Unpurified rabbit serum

Armazenamento e estabilidade

Maintain at -20°C in undiluted aliquots for up to 1 year date of receipt. Avoid repeated freeze/thaw cycles.

Nota de análise

Control
C2C12 cell lysates

Outras notas

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable