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Documentos Principais

06-237

Sigma-Aldrich

Anti-Gsα Antibody

serum, Upstate®

Sinônimo(s):

Anti-AHO, Anti-C20orf45, Anti-GNAS1, Anti-GPSA, Anti-GSA, Anti-GSP, Anti-NESP, Anti-PITA3, Anti-POH, Anti-SCG6, Anti-SgVI

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About This Item

Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

fonte biológica

rabbit

Nível de qualidade

100

forma do anticorpo

serum

tipo de produto de anticorpo

primary antibodies

clone

polyclonal

reatividade de espécies

mouse, human, bovine

fabricante/nome comercial

Upstate®

técnica(s)

immunocytochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

Isotipo

IgG

nº de adesão NCBI

NM_000516.4
NM_001077488.1
NM_001077489.1
NM_001077490.1
NM_016592.2
NM_080425.2
NM_080426.2

nº de adesão UniProt

Q5JWF2

Condições de expedição

dry ice

modificação pós-traducional do alvo

unmodified

Informações sobre genes

human ... GNAS(2778)

Especificidade

Recognizes the large and small forms of Gsα; does not cross-react with other G proteins.

Imunogênio

peptide corresponding to the c-terminus of bovine Gsα (RMHLRQYELL); this sequence is present in all three isoforms of human Gsα (Gsα1, Gsα2, and GsαXL)

Aplicação

Anti-Gsα Antibody is an antibody against Gsα for use in IC, IP & WB.
Research Category
Signaling
Research Sub Category
GPCR, cAMP/cGMP & Calcium Signaling

Qualidade

routinely evaluated by immunoblot on rat brain microsomal preparation (Catalog #12-144)

Descrição-alvo

large isoform (52 kDa) and small isoform (45 kDa)

Ligação

Replaces: AB1639

forma física

Protein A purified
Serum diluted 1:1 in PBS.

Armazenamento e estabilidade

Maintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Nota de análise

Control
Widely expressed

Outras notas

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Informações legais

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de classe de armazenamento

10 - Combustible liquids

Classe de risco de água (WGK)

WGK 2

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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Journal of Bone and Mineral Research null
Arrestin-3 is essential for the activation of Fyn by the luteinizing hormone receptor (LHR) in MA-10 cells.
Colette Galet,Mario Ascoli
Cellular Signalling null
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Endocrinology, 157(2), 497-507 (2015-12-17)
PTH regulates serum calcium, phosphate, and 1,25-dihydroxyvitamin D (1,25(OH)2D) levels by acting on bone and kidney. In renal proximal tubules (PTs), PTH inhibits reabsorption of phosphate and stimulates the synthesis of 1,25(OH)2D. The PTH receptor couples to multiple G proteins.
Bo Li et al.
FEBS letters, 587(5), 410-416 (2013-01-29)
β-Arrestins function to mediate G protein-coupled receptor (GPCR) desensitization and internalization and to initiate G protein independent signaling of GPCRs. Elucidating how β-arrestin and G protein signal pathways coordinate with each other is important to fully understand GPCR signaling. Here
Emma D O'Brien et al.
Developmental biology, 350(1), 80-88 (2010-12-04)
Sperm motility is essential for achieving fertilization. In animals with external fertilization as amphibians, spermatozoa are stored in a quiescent state in the testis. Spermiation to hypotonic fertilization media triggers activation of sperm motility. Bufo arenarum sperm are immotile in
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