878110P

C16-02:0 PC

Avanti Polar Lipids 878110P, powder

• Sinônimo(s): 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine
• Fórmula empírica (Notação de Hill): C₂₆H₅₄NO₇P
• Número CAS: 74389-68-7
• Peso molecular: 523.68
• Código UNSPSC: 12352211
• NACRES: NA.25

Propriedades

• forma: powder
• embalagem: pkg of 1 × 25 mg (878110P-25mg); pkg of 1 × 5 mg (878110P-5mg)
• fabricante/nome comercial: Avanti Polar Lipids 878110P
• tipo de lipídio: phosphoglycerides; bioactive lipids
• Condições de expedição: dry ice
• temperatura de armazenamento: −20°C
• cadeia de caracteres SMILES: [O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(C)=O)COCCCCCCCCCCCCCCCC)=O
• InChI: 1S/C26H54NO7P/c1-6-7-8-9-10-11-12-13-14-15-16-17-18-19-21-31-23-26(34-25(2)28)24-33-35(29,30)32-22-20-27(3,4)5/h26H,6-24H2,1-5H3/t26-/m1/s1
• chave InChI: HVAUUPRFYPCOCA-AREMUKBSSA-N

Descrição

Descrição geral

C16-02:0 PC, also referred as 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine (C16 PAF) (acetyl PAF), is a platelet-activating factor (PAF). Acetyl PAF is a natural PAF with ether-linked hexadecyl chain at the sn-1 position and an acetyl group at the sn-2 position.

Aplicação

C16-02:0 PC or 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine may be used as a substrate in enzymatic lipoprotein-associated phospholipase A2 (Lp-PLA2) activity assay. It may also be used to study its physicochemical properties and its interaction with peptides derived from the C-terminal domains of human apolipoprotein E.

Ações bioquímicas/fisiológicas

C16-02:0 PC, a platelet-activating factor and a lipid mediator is involved in various inflammatory diseases. It facilitates initiation and progression of atherosclerosis. PAF acts as a potential biomarker for coronary artery diseases. It exhibits its activity by binding to a specific PAF receptor, which belongs to the seven transmembrane-spanning G-protein-linked receptors family. PAF on hydrolysis by platelet-activating factor-acetyl hydrolase produces LysoPAF (1-O-alkyl-2-hydroxy-sn-glycero-3-phosphocholine).

Embalagem

5 mL Clear Glass Sealed Ampule (878110P-25mg)

5 mL Clear Glass Sealed Ampule (878110P-5mg)

Informações legais

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable