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858144P

Avanti

18:0 Lyso PS

1-stearoyl-2-hydroxy-sn-glycero-3-phospho-L-serine (sodium salt), powder

Sinônimo(s):

1-octadecanoyl-sn-glycero-3-phospho-L-serine (sodium salt); 18:0 LPS; C18 LPS; PS(18:0/0:0); 110725

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About This Item

Fórmula empírica (Notação de Hill):
C24H47NPO9Na
Número CAS:
1246298-16-7
Peso molecular:
547.59
Código UNSPSC:
51191904
NACRES:
NA.25

Ensaio

99% (LPS; may contain up to 15% of the 2-LPS isomer, TLC)

Formulário

powder

embalagem

pkg of 1 × 1 mg (858144P-1mg)
pkg of 1 × 5 mg (858144P-5mg)

fabricante/nome comercial

Avanti Research™ - A Croda Brand 858144P

tipo de lipídio

cardiolipins
phospholipids

Condições de expedição

dry ice

temperatura de armazenamento

−20°C

cadeia de caracteres SMILES

[H][C@@](COP([O-])(OC[C@](C([O-])=O)([H])[NH3+])=O)(O)COC(CCCCCCCCCCCCCCCCC)=O.[Na+]

InChI

1S/C24H48NO9P.Na/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-23(27)32-18-21(26)19-33-35(30,31)34-20-22(25)24(28)29;/h21-22,26H,2-20,25H2,1H3,(H,28,29)(H,30,31);/q;+1/p-1/t21-,22+;/m1./s1

chave InChI

SVSJEWKLQKWQOV-NSLUPJTDSA-M

Aplicação

18:0 Lyso PS has been used to stimulate the increase in intracellular cyclic adenosine monophosphate (cAMP) in G protein-coupled receptor 174 (GPR174)-cells. It may also be used in liquid chromatography-mass spectrometry (LC-MS) based structural characterization of oxygenated/hydrolyzed molecular species of phosphatidylserine (PS).

Embalagem

5 mL Amber Glass Screw Cap Vial (858144P-1mg)
5 mL Amber Glass Screw Cap Vial (858144P-5mg)

Informações legais

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Código de classe de armazenamento

11 - Combustible Solids

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Certificados de análise (COA)

Lot/Batch Number

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Kazuya Sugita et al.
Biochemical and biophysical research communications, 430(1), 190-195 (2012-11-28)
We established cell lines that stably express orphan GPCR GPR174 using CHO cells, and studied physiological and pharmacological features of the receptor. GPR174-expressing cells showed cell-cell adhesion with localization of actin filaments to cell membrane, and revealed significant delay of
Vladimir A Tyurin et al.
Biochemistry, 51(48), 9736-9750 (2012-11-15)
Ca(2+)-independent lipoprotein-associated phospholipase A(2) (Lp-PLA(2)) is a member of the phospholipase A(2) superfamily with a distinguishing characteristic of high specificity for oxidatively modified sn-2 fatty acid residues in phospholipids that has been especially well characterized for peroxidized species of phosphatidylcholines
Ming Zhu et al.
International immunopharmacology, 81, 106034-106034 (2019-12-02)
GPR174 plays a crucial role in immune responses, but the role of GPR174 in the pathological progress of sepsis remains incompletely understood. In this study, we generated a sepsis model by cecal ligation and puncture (CLP) to investigate the role
Masako Nishikawa et al.
Journal of atherosclerosis and thrombosis, 22(5), 518-526 (2014-12-03)
Lysophospholipids, particularly sphingosine 1-phosphate and lysophosphatidic acid, are known to be involved in the pathogenesis of atherosclerosis; however, the role of lysophosphatidylserine (LysoPS) in the onset of atherosclerotic diseases remains uncertain. We investigated the effects of LysoPS on the uptake

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