857323P

16:0 Cyclic LPA

1-palmitoyl-sn-glycero-2,3-cyclic-phosphate (ammonium salt), powder

• Sinônimo(s): 1-hexadecanoyl-sn-glycero-2,3-cyclic-phosphate (ammonium salt); cPA; cLPA
• Fórmula empírica (Notação de Hill): C₁₉H₄₀NO₆P
• Número CAS: 799268-71-6
• Peso molecular: 409.50
• Código UNSPSC: 51191904
• NACRES: NA.25

Propriedades

• Ensaio: >99% (TLC)
• Formulário: powder
• embalagem: pkg of 1 × 1 mg (857323P-1mg)
• fabricante/nome comercial: Avanti Research^™ - A Croda Brand 857323P
• tipo de lipídio: cardiolipins; phospholipids
• Condições de expedição: dry ice
• temperatura de armazenamento: −20°C
• cadeia de caracteres SMILES: O=P1([O-])O[C@H](COC(CCCCCCCCCCCCCCC)=O)CO1.[NH4+]
• chave InChI: NATIUIORRLVXDB-GMUIIQOCSA-N

Descrição

Descrição geral

Cyclic phosphatidic acid (cPA) is a naturally occurring analog of the growth factor-like phospholipid mediator, lysophosphatidic acid (LPA). The sn-2 hydroxy group of CPA forms a 5-membered ring with the sn-3 phosphate. cPA affects numerous cellular functions, including anti-mitogenic regulation of the cell cycle, induction of stress fiber formation, inhibition of tumor cell invasion and metastasis, and regulation of differentiation and survival of neuronal cells.
Interestingly, many of these cellular responses caused by cPA oppose those of LPA despite the activation of apparently overlapping receptor populations.

Aplicação

16:0 Cyclic LPA may be used for the extraction recovery of cyclic phosphatidic acid (cPA) at different pH conditions using Bligh-Dyer method.

Embalagem

5 mL Amber Glass Screw Cap Vial (857323P-1mg)

Informações legais

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3