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Documentos Principais

850368P

Avanti

20:0 PC

1,2-diarachidoyl-sn-glycero-3-phosphocholine, powder

Sinônimo(s):

1,2-dieicosanoyl-sn-glycero-3-phosphocholine; PC(20:0/20:0)

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About This Item

Fórmula empírica (Notação de Hill):
C48H96NO8P
Número CAS:
Peso molecular:
846.25
Número MDL:
Código UNSPSC:
51191904
NACRES:
NA.25

Ensaio

>99% (TLC)

Formulário

powder

embalagem

pkg of 1 × 200 mg (850368P-200mg)
pkg of 1 × 25 mg (850368P-25mg)
pkg of 1 × 500 mg (850368P-500mg)

fabricante/nome comercial

Avanti Research - A Croda Brand 850368P

tipo de lipídio

cardiolipins
phospholipids

Condições de expedição

dry ice

temperatura de armazenamento

−20°C

cadeia de caracteres SMILES

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCCCC)=O)=O

InChI

1S/C48H96NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-38-40-47(50)54-44-46(45-56-58(52,53)55-43-42-49(3,4)5)57-48(51)41-39-37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h46H,6-45H2,1-5H3/t46-/m1/s1

chave InChI

YKIOPDIXYAUOFN-YACUFSJGSA-N

Descrição geral

Phosphatidylcholine, a major source of diacylglycerol (DAG) is considered as a biological membrane lipid. 20:0 PC is a zwitterionic lipid.
The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.

Aplicação

20:0 PC may be used:
  • in the preparation of liposomes
  • to prepare vesicles or supported bilayer to study its ability in spontaneously forming distinct lipid domains, rafts and/or asymmetric bilayers along with other phosphatidylcholine lipids
  • to prepare small unilamellar vesicles (SUVs) to study the effect of hydrophobic mismatch on gramicidin conformation and organization

Ações bioquímicas/fisiológicas

Phosphatidylcholine (PC) can serve as a surfactant in the mucus.

Embalagem

20 mL Clear Glass Screw Cap Vial (850368P-500mg)
5 mL Amber Glass Screw Cap Vial (850368P-200mg)
5 mL Amber Glass Screw Cap Vial (850368P-25mg)

Informações legais

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable


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Certificados de análise (COA)

Lot/Batch Number

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Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 32(1), 46-52 (2013-07-23)
We investigated if mixtures of the phosphatidylcholine (PC) lipids 1,2-dilauroyl-sn-glycero-3-phosphocholine (C12:0 PC; DLPC) and 1,2-diarachidoyl-sn-glycero-3-phosphocholine (C20:0 PC; DAPC), which differ by eight methylene groups in acyl chain length, lead to the spontaneous formation of distinct lipid rafts and asymmetric bilayers.
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Nanoparticle-mediated drug delivery has long utilized PEGylation as a mechanism for reducing uptake by the reticuloendothelial system and extending circulation lifetimes. However, studies over the past 2 decades have established that immune responses to PEG can promote clearance on repeat injection

Global Trade Item Number

SKUGTIN
850368P-200MG4061835230563
850368P-25MG4061835230570
850368P-500MG4061835230587

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