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Documentos Principais

850373C

Avanti

24:0 PC

1,2-dilignoceroyl-sn-glycero-3-phosphocholine, chloroform

Sinônimo(s):

1,2-ditetracosanoyl-sn-glycero-3-phosphocholine; PC(24:0/24:0) ; 110929

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About This Item

Fórmula empírica (Notação de Hill):
C56H112NO8P
Número CAS:
Peso molecular:
958.46
Número MDL:
Código UNSPSC:
51191904
NACRES:
NA.25

Ensaio

>99% (TLC)

Formulário

liquid

embalagem

pkg of 1 × 2.5 mL (850373C-25mg)

fabricante/nome comercial

Avanti Research - A Croda Brand 850373C

concentração

10 mg/mL (850373C-25mg)

tipo de lipídio

phospholipids
cardiolipins

Condições de expedição

dry ice

temperatura de armazenamento

−20°C

Descrição geral

24:0 PC (1,2-dilignoceroyl-sn-glycero-3-phosphocholine) is a long-chain diacyl phospholipid, which has C24 saturated hydrocarbon chains. This lipid has a phosphatidylcholine (PC) headgroup.
The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.

Aplicação

24:0 PC (1,2-dilignoceroyl-sn-glycero-3-phosphocholine) may be used:
  • in short-chain micelles, longer-chain oriented multilayers and in Langmuir monolayers for structural studies
  • as an acyl chain lipid in microbubble condensed droplets (MCDs) and characterization studies
  • in phosphatidylcholine bilayer preparation for Raman spectroscopy studies

Ações bioquímicas/fisiológicas

Phosphatidylcholine (PC) can prevent the penetrance of bacteria by acting as a surfactant. This phospholipid is capable of forming a strong bilayer.

Embalagem

5 mL Clear Glass Sealed Ampule (850373C-25mg)

Informações legais

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Pictogramas

Skull and crossbonesHealth hazard

Palavra indicadora

Danger

Classificações de perigo

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Órgãos-alvo

Central nervous system, Liver,Kidney

Classe de risco de água (WGK)

WGK 3


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A A Dmitriev et al.
The journal of physical chemistry. B, 119(51), 15613-15622 (2015-11-27)
Raman scattering of five phosphatidylcholines [1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC), 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine (DPPC), 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC), 1,2-dilinoleoyl-sn-glycero-3-phosphocholine (DLPC), and 1,2-dilignoceroyl-sn-glycero-3-phosphocholine (PC24)] was studied in a wide temperature range. These phospholipid bilayers differ in the temperature of the gel-fluid transition Tm (from -57 to +80 °C)
Inflammatory Bowel Disease
Parian AM, et al.
Integrative Medicine, 501-516 (2018)
Paul A Mountford et al.
Langmuir : the ACS journal of surfaces and colloids, 31(16), 4627-4634 (2015-04-09)
This study explored the thermal conditions necessary for the vaporization of superheated perfluorocarbon nanodrops. Droplets C3F8 and C4F10 coated with a homologous series of saturated diacylphosphatidylcholines were formed by condensation of 4 μm diameter microbubbles. These drops were stable at
Marcus O W Grimm et al.
International journal of molecular sciences, 14(3), 5879-5898 (2013-03-15)
Alzheimer's disease (AD) is characterized by extracellular accumulation of amyloid-β peptide (Aβ), generated by proteolytic processing of the amyloid precursor protein (APP) by β- and γ-secretase. Aβ generation is inhibited when the initial ectodomain shedding is caused by α-secretase, cleaving

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