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Key Documents

840037P

Avanti

16:0 PS

Avanti Research - A Croda Brand

Sinônimo(s):

1,2-dihexadecanoyl-sn-glycero-3-phospho-L-serine (sodium salt); DPPS; PS(16:0/16:0); 110668

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About This Item

Fórmula empírica (Notação de Hill):
C38H73NO10PNa
Número CAS:
Peso molecular:
757.95
Código UNSPSC:
51191904
NACRES:
NA.25

descrição

1,2-dipalmitoyl-sn-glycero-3-phospho-L-serine (sodium salt)

Ensaio

>99% (TLC)

forma

powder

embalagem

pkg of 1 × 10 mg (840037P-10mg)
pkg of 1 × 200 mg (840037P-200mg)
pkg of 1 × 25 mg (840037P-25mg)
pkg of 1 × 500 mg (840037P-500mg)

fabricante/nome comercial

Avanti Research - A Croda Brand

tipo de lipídio

phospholipids
cardiolipins

Condições de expedição

dry ice

temperatura de armazenamento

−20°C

cadeia de caracteres SMILES

[H][C@@](COP([O-])(OC[C@](C([O-])=O)([H])[NH3+])=O)(OC(CCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O.[Na+]

InChI

1S/C38H74NO10P.Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-36(40)46-31-34(32-47-50(44,45)48-33-35(39)38(42)43)49-37(41)30-28-26-24-22-20-18-16-14-12-10-8-6-4-2;/h34-35H,3-33,39H2,1-2H3,(H,42,43)(H,44,45);/q;+1/p-1/t34-,35+;/m1./s1

chave InChI

GTLXLANTBWYXGW-CEGNZRHUSA-M

Descrição geral

Phosphatidylserine (PtdSer) is an anionic phospholipid abundantly present in the eukaryotic cell. 10% of the total cellular lipid consists of phosphatidylserine. O‐phospho‐L‐serine is a heat‐stable substrate.

Aplicação

16:0 PS has been used in the assay to measure interactions between purified dynamin-related protein 1 (Drp1) and synthetic liposomes.
16:0 PS may be used in liposome flotation assay to measure its interactions between purified dynamin related protein 1 (Drp1) and as a component in the lipid mixtures to prepare lipid monolayers. It has also been used to prepare liposomes by the lipid film hydration method.

Ações bioquímicas/fisiológicas

Phosphatidylserine (PtdSer) participates in various intracellular signaling pathways. It also play a major role in apoptosis and blood clotting.

Embalagem

20 mL Clear Glass Screw Cap Vial (840037P-200mg)
30 mL Amber Wide Mouth Bottle with Screw Cap (840037P-500mg)
5 mL Amber Glass Screw Cap Vial (840037P-10mg)
5 mL Amber Glass Screw Cap Vial (840037P-25mg)

Informações legais

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Código de classe de armazenamento

11 - Combustible Solids


Certificados de análise (COA)

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Condensation of Model Lipid Films by Cholesterol: Specific Ion Effects
Martimathin-MA, et al.
Coatings, 9(8), 474-474 (2020)
Assay to Measure Interactions between Purified Drp1 and Synthetic Liposomes
Adachi Y, et al.
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Tumor cells require high rates of lipid synthesis to support membrane biogenesis for their exacerbated growth. The only two proteins known that activate phospholipid synthesis are Fra-1 and c-Fos, two members of the AP-1 family of transcription factors. These proteins
Koshiki Mino et al.
FEBS letters, 551(1-3), 133-138 (2003-09-11)
O-Acetylserine sulfhydrylase (OASS), a pyridoxal 5'-phosphate (PLP)-dependent enzyme, catalyzes the synthesis of L-cysteine from O-acetyl-L-serine and sulfide. O-Acetyl-L-serine is labile at high temperatures at which hyperthermophilic archaea live. Herein, a study of the substrate specificity of OASS from Aeropyrum pernix
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The journal of physical chemistry letters, 10(22), 7195-7199 (2019-11-05)
We investigate the interaction between highly charged lipid bilayers in the presence of monovalent counterions. Neutron and X-ray reflectivity experiments show that the water layer between like-charged bilayers is thinner than for zwitterionic lipids, demonstrating the existence of counterintuitive electrostatic

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