810250C

25-NBD Cholesterol

Avanti Research^™ - A Croda Brand 810250C

• Sinônimo(s): 25-[N-[(7-nitro-2-1,3-benzoxadiazol-4-yl)methyl]amino]-27-norcholesterol
• Fórmula empírica (Notação de Hill): C₃₃H₄₈N₄O₄
• Número CAS: 105539-27-3
• Peso molecular: 564.76
• Código UNSPSC: 12352211
• NACRES: NA.25

Propriedades

• Ensaio: >99% (TLC)
• Formulário: liquid
• embalagem: pkg of 1 × 1 mL (810250C-10mg); pkg of 1 × 1 mL (810250C-1mg); pkg of 1 × 1 mL (810250C-5mg)
• fabricante/nome comercial: Avanti Research^™ - A Croda Brand 810250C
• concentração: 1 mg/mL (810250C-1mg); 10 mg/mL (810250C-10mg); 5 mg/mL (810250C-5mg)
• Condições de expedição: dry ice
• temperatura de armazenamento: −20°C
• InChI: 1S/C33H48N4O4/c1-20(7-6-8-21(2)36(5)28-13-14-29(37(39)40)31-30(28)34-41-35-31)25-11-12-26-24-10-9-22-19-23(38)15-17-32(22,3)27(24)16-18-33(25,26)4/h9,13-14,20-21,23-27,38H,6-8,10-12,15-19H2,1-5H3/t20-,21?,23+,24+,25+,26+,27+,32+,33-/m1/s1
• chave InChI: RMGLSQAGXRZCPZ-OVHOIDCTSA-N

Descrição

Descrição geral

25-NBD Cholesterol is a fluorescent derivative of cholesterol. Its fluorescent property is due to presence of NBD (2-(4-nitro-2,1,3-benzoxadiazol-7-yl) aminoethyl) group.

Aplicação

25-NBD Cholesterol can be used as a labeling agent for confocal microscopy in studying endosomal trafficking and vesicle formation.

Ações bioquímicas/fisiológicas

Cholesterol is synthesized via a cascade of enzymatic reactions known as the mevalonate pathway. Cholesterol plays a major role in the architecture and stability of the plasma membrane and is also involved in the synthesis of cholecalciferol (Vitamin D3). Cholesterol build up on the walls or arteries causes obstruction of blood flow leading to a serious condition called artherosclerosis. It is a precursor for bile acid and for the synthesis of steroid hormones like progesterone, testosterone, cortisol, and aldosterone.

Embalagem

5 mL Clear Glass Sealed Ampule (810250C-10mg)

5 mL Clear Glass Sealed Ampule (810250C-1mg)

5 mL Clear Glass Sealed Ampule (810250C-5mg)

Informações legais

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Informações de segurança

• Pictogramas: GHS06,GHS08
• Palavra indicadora: Danger
• Frases de perigo: H302,H315,H319,H331,H336,H351,H361d,H372
• Declarações de precaução: P202 - P301 + P312 - P302 + P352 - P304 + P340 + P311 - P305 + P351 + P338 - P308 + P313
• Classificações de perigo: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3
• Órgãos-alvo: Liver,Kidney, Respiratory system
• Código de classe de armazenamento: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): does not flash
• Ponto de fulgor (°C): does not flash