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Documentos Principais

700175P

Avanti

Brassicasterol

Avanti Research - A Croda Brand

Sinônimo(s):

24-Methyl cholest-5,22-dien-3β-ol

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About This Item

Fórmula empírica (Notação de Hill):
C28H46O
Número CAS:
Peso molecular:
398.66
Código UNSPSC:
12352211
NACRES:
NA.25

Ensaio

>99% (TLC)

Formulário

powder

embalagem

pkg of 1 × 5 mg (700175P-5MG)

fabricante/nome comercial

Avanti Research - A Croda Brand

Condições de expedição

dry ice

temperatura de armazenamento

−20°C

cadeia de caracteres SMILES

CC1(CC[C@H](O)C2)C2=CCC3C1CCC4(C)C3CCC4C(/C=C/[C@H](C)C(C)C)C

InChI

1S/C28H46O/c1-18(2)19(3)7-8-20(4)24-11-12-25-23-10-9-21-17-22(29)13-15-27(21,5)26(23)14-16-28(24,25)6/h7-9,18-20,22-26,29H,10-17H2,1-6H3/b8-7+/t19-,20+,22-,23-,24+,25-,26-,27-,28+/m0/s1

chave InChI

OILXMJHPFNGGTO-ZAUYPBDWSA-N

Descrição geral

Brassicasterol is a plant sterol, sharing similar structure with cholesterol. It is obtained through the dietary sources, including sea food.

Aplicação


  • Deciphering the effect of phytosterols on Alzheimer′s disease and Parkinson′s disease: the mediating role of lipid profiles: This research demonstrates the neuroprotective potential of phytosterols, including Brassicasterol, in modulating lipid profiles to mitigate symptoms of neurodegenerative diseases such as Alzheimer′s and Parkinson′s (Guo et al., 2024).

  • Liposomal Phytosterols as LDL-Cholesterol-Lowering Agents in Diet-Induced Hyperlipidemia: Discusses the effectiveness of Brassicasterol and other phytosterols encapsulated in liposomes for reducing LDL cholesterol, showcasing a potential therapeutic approach in hyperlipidemia management (Poudel et al., 2023).

  • Sterol Regulation of Development and 20-Hydroxyecdysone Biosynthetic and Signaling Genes in Drosophila melanogaster: Highlights the role of Brassicasterol in regulating developmental and hormonal pathways in model organisms, suggesting implications for developmental biology studies (Wen et al., 2023).

Ações bioquímicas/fisiológicas

Brassica sterol in cerebrospinal fluid might serve as an indicator for Alzheimer′s disease. It is found in rapeseed oil. Brassicasterol is thus, useful in identifying brassica oil and contamination of rapeseed and canola oil in others. Plant sterols can penetrate through the blood brain barrier.

Embalagem

5 mL Amber Glass Screw Cap Vial (700175P-5MG)

Informações legais

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable


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Certificados de análise (COA)

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Analysis of sterol compounds from Sambucus ebulus
Bubulica MV, et al.
Chemistry of Natural Compounds, 1-2 (2012)
Rapeseed and Canola Oil: Production, Processing, Properties and Uses, 60-60 (2004)
The plant sterol brassicasterol as additional CSF biomarker in Alzheimer?s disease
Vanmierlo T, et al.
Acta Psychiatrica Scandinavica, 124(3), 184-192 (2011)
The search of new biomarkers to identify Alzheimer?s disease: An editorial comment to T. Vanmierlo et al.`The plant sterol brassicasterol and additional CFS biomarker in Alzheimer?s Disease?(1)
Lobo A and Quintanilla MA
Acta Psychiatrica Scandinavica, 124(3), 163-164 (2011)

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