700016P

cholesterol sulfate

Avanti Polar Lipids 700016P

• Sinônimo(s): cholesterol sulfonate; cholesteryl sulfate; sodium cholesteryl sulfate; cholesteryl sulphate
• Fórmula empírica (Notação de Hill): C₂₇H₄₅NaO₄S
• Número CAS: 2864-50-8
• Peso molecular: 488.70
• Código UNSPSC: 12352211
• NACRES: NA.25

Propriedades

• descrição: cholesterol 3-sulfate (sodium salt)
• Ensaio: >99% (TLC)
• forma: powder
• embalagem: pkg of 1 × 1 g (700016P-1g); pkg of 1 × 25 mg (700016P-25mg); pkg of 1 × 500 mg (700016P-500mg)
• fabricante/nome comercial: Avanti Polar Lipids 700016P
• Condições de expedição: dry ice
• temperatura de armazenamento: −20°C
• InChI: 1S/C27H46O4S.Na/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(31-32(28,29)30)13-15-26(20,4)25(22)14-16-27(23,24)5;/h9,18-19,21-25H,6-8,10-17H2,1-5H3,(H,28,29,30);/q;+1/p-1/t19-,21+,22+,23-,24+,25+,26+,27-;/m1./s1
• chave InChI: LMPVQXVJTZWENW-KPNWGBFJSA-M

Descrição

Descrição geral

Cholesterol sulfate is synthesized by the sulfoconjugation of cholesterol in the presence of enzyme cholesterol sulfotransferase. It is present in brain, lungs, hair and skin tissues as well as cells including erythrocytes, platelets and spermatozoa.

Aplicação

Cholesterol sulfate has been used in micelle preparation and in surface plasmon resonance (SPR) studies.

Ações bioquímicas/fisiológicas

Cholesterol sulfate is associated with atherosclerotic lesions and serves as a substrate for platelet adhesion. It stabilizes the spermatozoa membranes and erythrocytes. Cholesterol sulfate is involved in the keratinocyte differentiation and its levels are elevated in recessive X-linked ichthyosis. It serves as a ligand for retinoic acid-related orphan receptor α (RORα). Cholesterol sulfate regulates glucose metabolism and is a potential target for metabolic disorders. It is also a potential marker for human uterine cervical carcinoma tissue and prostate carcinoma.

Embalagem

20 mL Clear Glass Screw Cap Vial (700016P-1g)

20 mL Clear Glass Screw Cap Vial (700016P-500mg)

5 mL Amber Glass Screw Cap Vial (700016P-25mg)

Informações legais

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable