QBD10319

m-dPEG^®₂₄-MAL

• Sinônimo(s): Polyethylene glycol
• Fórmula empírica (Notação de Hill): C₅₆H₁₀₆N₂O₂₇
• Peso molecular: 1239.44
• Número MDL: MFCD11041164
• Código UNSPSC: 51171641
• ID de substância PubChem: 329823917
• NACRES: NA.22

Propriedades

• Ensaio: >90%
• Formulário: solid or viscous liquid
• adequação da reação: reactivity: thiol reactive; reagent type: chemical modification reagent; reagent type: cross-linking reagent; reactivity: sulfhydryl reactive
• arquitetura do polímero: shape: linear; functionality: monofunctional
• Condições de expedição: ambient
• temperatura de armazenamento: −20°C
• cadeia de caracteres SMILES: O=C(NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC)CCN1C(C=CC1=O)=O
• InChI: 1S/C56H106N2O27/c1-62-8-9-64-12-13-66-16-17-68-20-21-70-24-25-72-28-29-74-32-33-76-36-37-78-40-41-80-44-45-82-48-49-84-52-53-85-51-50-83-47-46-81-43-42-79-39-38-77-35-34-75-31-30-73-27-26-71-23-22-69-19-18-67-15-14-65-11-10-63-7-5-57-54(59)4-6-58-55(60)2-
• chave InChI: IRQWFNZIEAPTBJ-UHFFFAOYSA-N

Descrição

Características e benefícios

The m-dPEG^®₂₄-MAL provides a variety of means to modify small molecules, peptides, proteins, and functionalized surfaces (metals, glass, and others). The single molecular weight methoxy-terminated dPEG^® molecules are hydrophilic and non-immunogenic of exact length. Modification with m-dPEG^® reagents can improve water solubility, increase hydrodynamic volume, eliminate or reduce non-specific binding, protect peptides and proteins from proteolysis, reduce or eliminate immunogenicity, and increase serum half-life in vivo. The m-dPEG^®₂₄-MAL reacts with free sulfhydryls in a rapid, highly specific reaction in aqueous media at pH 6.5-7.5.

Informações legais

Products Protected under U.S. Patents # 7,888,536 B2

dPEG is a registered trademark of Quanta BioDesign

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable